User profiles for Hala Muaddi
Hala MuaddiMD, MSc, PhD, FRCSC Verified email at mail.utoronto.ca Cited by 1331 |
Clinical outcomes of robotic surgery compared to conventional surgical approaches (laparoscopic or open): a systematic overview of reviews
Objective: Describe clinical outcomes (eg, postoperative complications, survival) after robotic
surgery compared to open or laparoscopic surgery. Background: Robotic surgery utilization …
surgery compared to open or laparoscopic surgery. Background: Robotic surgery utilization …
The impact of negative pressure wound therapy for closed surgical incisions on surgical site infection: a systematic review and meta-analysis
Background Surgical site infections cause substantial morbidity and mortality. Negative
pressure wound therapy may reduce the risk of surgical site infections, but current evidence is …
pressure wound therapy may reduce the risk of surgical site infections, but current evidence is …
[HTML][HTML] The new era of transplant oncology: liver transplantation for nonresectable colorectal cancer liver metastases
A Gorgen, H Muaddi, W Zhang, I McGilvray… - Canadian Journal of …, 2018 - hindawi.com
Colorectal cancer (CRC) is the third most incident cancer worldwide. Most of CRC patients
will develop distant metastases, mainly to the liver, and liver resection is the only potential …
will develop distant metastases, mainly to the liver, and liver resection is the only potential …
Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response
Purpose: Tumor hypoxia is a negative prognostic factor in multiple cancers, due in part to its
role in causing resistance to radiotherapy. Hypoxia arises in tumor regions distal to blood …
role in causing resistance to radiotherapy. Hypoxia arises in tumor regions distal to blood …
Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency
H Muaddi, M Majumder, P Peidis… - Molecular biology of …, 2010 - Am Soc Cell Biol
Various forms of stress induce pathways that converge on the phosphorylation of the alpha (α)
subunit of eukaryotic translation initiation factor eIF2 at serine 51 (S51), a modification that …
subunit of eukaryotic translation initiation factor eIF2 at serine 51 (S51), a modification that …
Outcomes of radiofrequency ablation as first-line therapy for hepatocellular carcinoma less than 3 cm in potentially transplantable patients
Background & Aims Radiofrequency ablation (RFA) is an effective treatment for single
hepatocellular carcinoma (HCC) ≤3 cm. Disease recurrence is common, and in some patients …
hepatocellular carcinoma (HCC) ≤3 cm. Disease recurrence is common, and in some patients …
eIF2α Kinase PKR modulates the hypoxic response by Stat3-dependent transcriptional suppression of HIF-1α
AI Papadakis, E Paraskeva, P Peidis, H Muaddi, S Li… - Cancer research, 2010 - AACR
Hypoxia within the tumor microenvironment promotes angiogenesis, metabolic reprogramming,
and tumor progression. In addition to activating hypoxia-inducible factor-1α (HIF-1α), …
and tumor progression. In addition to activating hypoxia-inducible factor-1α (HIF-1α), …
Association between social determinants of health and rates of liver transplantation in individuals with cirrhosis
JA Flemming, H Muaddi, M Djerboua, P Neves… - …, 2022 - Wiley Online Library
Background and Aims This study evaluated the association between neighborhood‐level
social determinants of health (SDOH) and liver transplantation (LT) among patients with …
social determinants of health (SDOH) and liver transplantation (LT) among patients with …
Safety and feasibility of initiating a hepatic artery infusion pump chemotherapy program for unresectable colorectal liver metastases: A multicenter, retrospective cohort …
H Muaddi, M D'Angelica, JT Wiseman… - Journal of surgical …, 2021 - Wiley Online Library
Introduction Hepatic artery infusion pump (HAIP) chemotherapy is a specialized therapy for
patients with unresectable colorectal liver metastases (uCRLM). Its effectiveness was …
patients with unresectable colorectal liver metastases (uCRLM). Its effectiveness was …
[HTML][HTML] The management of post-transplantation recurrence of hepatocellular carcinoma
…, T Ivanics, MPAW Claasen, H Muaddi… - Clinical and …, 2022 - ncbi.nlm.nih.gov
The annual incidence of hepatocellular carcinoma (HCC) continues to rise. Over the last
two decades, liver transplantation (LT) has become the preferable treatment of HCC, when …
two decades, liver transplantation (LT) has become the preferable treatment of HCC, when …