[HTML][HTML] Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism

Y Yang, PJ Hsu, YS Chen, YG Yang - Cell research, 2018 - nature.com
N 6 -methyladenosine (m 6 A) is a chemical modification present in multiple RNA species,
being most abundant in mRNAs. Studies on enzymes or factors that catalyze, recognize, and …

[HTML][HTML] Cancer stem cells (CSCs) in drug resistance and their therapeutic implications in cancer treatment

LTH Phi, IN Sari, YG Yang, SH Lee, N Jun… - Stem cells …, 2018 - hindawi.com
Cancer stem cells (CSCs), also known as tumor-initiating cells (TICs), are suggested to be
responsible for drug resistance and cancer relapse due in part to their ability to self-renew …

N6-Methyl-Adenosine (m6A) in RNA: An Old Modification with A Novel Epigenetic Function

…, YS Wu, MM Li, XJ Wang, YG Yang - Genomics, Proteomics …, 2013 - academic.oup.com
N 6 -methyl-adenosine (m 6 A) is one of the most common and abundant modifications on
RNA molecules present in eukaryotes. However, the biological significance of m 6 A …

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

…, Y Yang, C Yi, T Lindahl, T Pan, YG Yang… - Nature chemical …, 2011 - nature.com
We report here that fat mass and obesity-associated protein (FTO) has efficient oxidative
demethylation activity targeting the abundant N6-methyladenosine (m 6 A) residues in RNA in …

[PDF][PDF] ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility

…, X Zhao, J Liu, HE Krokan, A Klungland, YG Yang… - Molecular cell, 2013 - cell.com
N 6 -methyladenosine (m 6 A) is the most prevalent internal modification of messenger RNA
(mRNA) in higher eukaryotes. Here we report ALKBH5 as another mammalian demethylase …

Voluntary nonfinancial disclosure and the cost of equity capital: The initiation of corporate social responsibility reporting

…, OZ Li, A Tsang, YG Yang - The accounting …, 2011 - publications.aaahq.org
We examine a potential benefit associated with the initiation of voluntary disclosure of corporate
social responsibility (CSR) activities: a reduction in firms’ cost of equity capital. We find …

[HTML][HTML] Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

…, YL Zhao, X Wang, JMR Danielsen, F Liu, YG Yang - Cell research, 2014 - nature.com
The methyltransferase like 3 (METTL3)-containing methyltransferase complex catalyzes the
N6-methyladenosine (m6A) formation, a novel epitranscriptomic marker; however, the …

[PDF][PDF] Nuclear m6A reader YTHDC1 regulates mRNA splicing

…, HL Wang, Q Zhou, XJ Wang, YL Zhao, YG Yang - Molecular cell, 2016 - cell.com
The regulatory role of N 6 -methyladenosine (m 6 A) and its nuclear binding protein YTHDC1
in pre-mRNA splicing remains an enigma. Here we show that YTHDC1 promotes exon …

Nonfinancial disclosure and analyst forecast accuracy: International evidence on corporate social responsibility disclosure

…, S Radhakrishnan, A Tsang, YG Yang - The accounting …, 2012 - publications.aaahq.org
We examine the relationship between disclosure of nonfinancial information and analyst
forecast accuracy using firm-level data from 31 countries. We use the issuance of stand-alone …

[HTML][HTML] FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis

X Zhao, Y Yang, BF Sun, Y Shi, X Yang, W Xiao… - Cell research, 2014 - nature.com
The role of Fat Mass and Obesity-associated protein (FTO) and its substrate N6-methyladenosine
(m 6 A) in mRNA processing and adipogenesis remains largely unknown. We show …