Proinflammatory cytokines induce crosstalk between colonic epithelial cells and subepithelial myofibroblasts: implication in intestinal fibrosis

I Drygiannakis, V Valatas, O Sfakianaki… - Journal of Crohn's …, 2013 - academic.oup.com
Background and aims: Colonic epithelial cells and adjacent subepithelial myofibroblasts
are important counterparts in the pathogenesis of intestinal inflammation and fibrosis. We …

[HTML][HTML] Peri-nuclear antibodies correlate with survival in Greek primary biliary cirrhosis patients

O Sfakianaki, M Koulentaki, M Tzardi… - World Journal of …, 2010 - ncbi.nlm.nih.gov
AIM: To investigate possible associations of anti-nuclear envelope antibody (ANEA) with
disease severity and survival in Greek primary biliary cirrhosis (PBC) patients. METHODS: …

[HTML][HTML] Presence of disease specific autoantibodies against liver sinusoidal cells in primary biliary cirrhosis

O Sfakianaki, M Tzardi, A Voumvouraki… - World journal of …, 2013 - ncbi.nlm.nih.gov
AIM: To investigate the presence of autoantibodies directed against liver sinusoidal cells in
primary biliary cirrhosis (PBC). METHODS: Liver biopsies from 21 PBC patients were studied …

Octreotide modulates the effects on fibrosis of TNF-α, TGF-β and PDGF in activated rat hepatic stellate cells

S Klironomos, G Notas, O Sfakianaki, F Kiagiadaki… - Regulatory peptides, 2014 - Elsevier
Background and aims Somatostatin and its analogs may influence hepatic fibrosis
interfering through several mechanisms. The aim of this study was to investigate the effect of …

[HTML][HTML] Differences in telomerase activity between colon and rectal cancer

…, M Georgiadou, O Sfakianaki… - Canadian Journal of …, 2014 - ncbi.nlm.nih.gov
Background Colorectal cancer is one of the most common cancers and the third leading
cause of cancer death in both sexes. The disease progresses as a multistep process and is …

[HTML][HTML] Inhibitory control, task/rule switching, and cognitive planning in vascular dementia: are there any differences from vascular aging?

K Pantsiou, O Sfakianaki, V Papaliagkas… - Frontiers in aging …, 2018 - frontiersin.org
Recent studies have shown that patients diagnosed with Vascular Dementia (VaD) exhibit
deficits in executive functions. According to “vascular hypothesis of cognitive aging,” …

Serum surrogate markers of liver fibrosis in primary biliary cirrhosis

…, M Koulentaki, G Notas, O Sfakianaki… - European Journal of …, 2011 - Elsevier
BACKGROUND: Hyaluronan, leptin, laminin and collagen IV have been used extensively
for the assessment of liver fibrosis. The aim of this study was to assay these markers in the …

[HTML][HTML] Effects of octreotide and insulin on colon cancer cellular proliferation and correlation with hTERT activity

…, I Drygiannakis, M Georgiadou, O Sfakianaki… - …, 2014 - ncbi.nlm.nih.gov
Peptide hormone somatostatin and its receptors have a wide range of physiological functions
and play a role in the treatment of numerous human diseases, including colorectal cancer. …

[HTML][HTML] Increased ΤGF-β3 in primary biliary cirrhosis: An abnormality related to pathogenesis?

…, M Koulentaki, M Tzardi, O Sfakianaki… - World Journal of …, 2010 - ncbi.nlm.nih.gov
AIM: To investigate the transforming growth factor-β (TGF-β) isoforms in the peripheral and
hepatic venous blood of primary biliary cirrhosis (PBC) patients. METHODS: We examined …

Prevalence of thiopurine S-methyltransferase gene polymorphisms in patients with inflammatory bowel disease from the island of Crete, Greece

…, G Goulielmos, O Sfakianaki… - European Journal of …, 2017 - journals.lww.com
Background There is evidence that genotyping for the thiopurine S-methyltransferase (TPMT)
gene variants is useful for the prediction of response to thiopurine analogs (azathioprine …