User profiles for P. Sullivan

Patrick F Sullivan

Professor of Genetics, University of North Carolina; Professor, MEB, Karolinska Institutet
Verified email at med.unc.edu
Cited by 153093

Genetic epidemiology of major depression: review and meta-analysis

PF Sullivan, MC Neale… - American journal of …, 2000 - Am Psychiatric Assoc
OBJECTIVE: The authors conducted a meta-analysis of relevant data from primary studies
of the genetic epidemiology of major depression.METHOD: The authors searched MEDLINE …

Genetic architectures of psychiatric disorders: the emerging picture and its implications

PF Sullivan, MJ Daly, M O'donovan - Nature Reviews Genetics, 2012 - nature.com
… Supporting the hypothesis that this association implicates MIR137, predicted targets of
miR-137 were significantly enriched for smaller GWAS P values (P < 0.01), and four of the genes …

Electric field poled organic electro-optic materials: state of the art and future prospects

LR Dalton, PA Sullivan, DH Bale - Chemical reviews, 2010 - ACS Publications
… In the case of an isolated chromophore, the polarization, p, of electron density that occurs
in response to a relatively weak electromagnetic field may be described by the relation (5) …

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

…, CM Hultman, P Lichtenstein, EF Thelander, P Sullivan… - Nature, 2009 - nature.com
P values, increasing proportions will be detected at increasingly liberal significance thresholds
(P T ), for example, P T < 0.1 or P T … alleles at different association test P T thresholds. For …

Biological insights from 108 schizophrenia-associated genetic loci

…, JR Wendland, T Werge, MJ Daly, PF Sullivan… - Nature, 2014 - nature.com
Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of
alleles, including common alleles of small effect that might be detected by genome-wide …

[HTML][HTML] Analysis of protein-coding genetic variation in 60,706 humans

…, D Saleheen, JM Scharf, P Sklar, PF Sullivan… - Nature, 2016 - nature.com
Large-scale reference data sets of human genetic variation are critical for the medical and
functional interpretation of DNA sequence changes. Here we describe the aggregation and …

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

…, CDA Stehouwer, M Stumvoll, P Sullivan… - Nature …, 2021 - nature.com
Trait-associated genetic variants affect complex phenotypes primarily via regulatory mechanisms
on the transcriptome. To investigate the genetics of gene expression, we performed cis…

[HTML][HTML] A comparison of sustained-release bupropion and placebo for smoking cessation

…, CR Sullivan, IT Croghan, PM Sullivan - … England Journal of …, 1997 - Mass Medical Soc
Background and Methods Trials of antidepressant medications for smoking cessation have
had mixed results. We conducted a double-blind, placebo-controlled trial of a sustained-…

[HTML][HTML] Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

…, ES Lander, PF Sullivan, P Sklar… - … England Journal of …, 2014 - Mass Medical Soc
Background Cancers arise from multiple acquired mutations, which presumably occur over
many years. Early stages in cancer development might be present years before cancers …

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

…, R Schachar, P Sklar, EJS Sonuga-Barke, PF Sullivan… - Nature …, 2019 - nature.com
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …