User profiles for P. Sullivan
Patrick F SullivanProfessor of Genetics, University of North Carolina; Professor, MEB, Karolinska Institutet Verified email at med.unc.edu Cited by 153093 |
Genetic epidemiology of major depression: review and meta-analysis
PF Sullivan, MC Neale… - American journal of …, 2000 - Am Psychiatric Assoc
OBJECTIVE: The authors conducted a meta-analysis of relevant data from primary studies
of the genetic epidemiology of major depression.METHOD: The authors searched MEDLINE …
of the genetic epidemiology of major depression.METHOD: The authors searched MEDLINE …
Genetic architectures of psychiatric disorders: the emerging picture and its implications
… Supporting the hypothesis that this association implicates MIR137, predicted targets of
miR-137 were significantly enriched for smaller GWAS P values (P < 0.01), and four of the genes …
miR-137 were significantly enriched for smaller GWAS P values (P < 0.01), and four of the genes …
Electric field poled organic electro-optic materials: state of the art and future prospects
LR Dalton, PA Sullivan, DH Bale - Chemical reviews, 2010 - ACS Publications
… In the case of an isolated chromophore, the polarization, p, of electron density that occurs
in response to a relatively weak electromagnetic field may be described by the relation (5) …
in response to a relatively weak electromagnetic field may be described by the relation (5) …
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
…, CM Hultman, P Lichtenstein, EF Thelander, P Sullivan… - Nature, 2009 - nature.com
… P values, increasing proportions will be detected at increasingly liberal significance thresholds
(P T ), for example, P T < 0.1 or P T … alleles at different association test P T thresholds. For …
(P T ), for example, P T < 0.1 or P T … alleles at different association test P T thresholds. For …
Biological insights from 108 schizophrenia-associated genetic loci
Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of
alleles, including common alleles of small effect that might be detected by genome-wide …
alleles, including common alleles of small effect that might be detected by genome-wide …
[HTML][HTML] Analysis of protein-coding genetic variation in 60,706 humans
Large-scale reference data sets of human genetic variation are critical for the medical and
functional interpretation of DNA sequence changes. Here we describe the aggregation and …
functional interpretation of DNA sequence changes. Here we describe the aggregation and …
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
Trait-associated genetic variants affect complex phenotypes primarily via regulatory mechanisms
on the transcriptome. To investigate the genetics of gene expression, we performed cis…
on the transcriptome. To investigate the genetics of gene expression, we performed cis…
[HTML][HTML] A comparison of sustained-release bupropion and placebo for smoking cessation
…, CR Sullivan, IT Croghan, PM Sullivan - … England Journal of …, 1997 - Mass Medical Soc
Background and Methods Trials of antidepressant medications for smoking cessation have
had mixed results. We conducted a double-blind, placebo-controlled trial of a sustained-…
had mixed results. We conducted a double-blind, placebo-controlled trial of a sustained-…
[HTML][HTML] Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence
…, ES Lander, PF Sullivan, P Sklar… - … England Journal of …, 2014 - Mass Medical Soc
Background Cancers arise from multiple acquired mutations, which presumably occur over
many years. Early stages in cancer development might be present years before cancers …
many years. Early stages in cancer development might be present years before cancers …
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …