Phosphorylated caveolin-1 regulates Rho/ROCK-dependent focal adhesion dynamics and tumor cell migration and invasion

B Joshi, SS Strugnell, JG Goetz, LD Kojic, ME Cox… - Cancer research, 2008 - AACR
Rho/ROCK signaling and caveolin-1 (Cav1) are implicated in tumor cell migration and
metastasis; however, the underlying molecular mechanisms remain poorly defined. Cav1 was …

[HTML][HTML] Diagnostic utility of galectin-3 in thyroid cancer

CG Chiu, SS Strugnell, OL Griffith, SJM Jones… - The American journal of …, 2010 - Elsevier
Galectin-3 (Gal-3), which has received significant recent attention for its utility as a diagnostic
marker for thyroid cancer, represents the most well-studied molecular candidate for thyroid …

Concerted regulation of focal adhesion dynamics by galectin-3 and tyrosine-phosphorylated caveolin-1

JG Goetz, B Joshi, P Lajoie, SS Strugnell… - The Journal of cell …, 2008 - rupress.org
Both tyrosine-phosphorylated caveolin-1 (pY14Cav1) and GlcNAc-transferase V (Mgat5) are
linked with focal adhesions (FAs); however, their function in this context is unknown. Here, …

Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation

B Joshi, M Bastiani, SS Strugnell, C Boscher… - Journal of Cell …, 2012 - rupress.org
Caveolin-1 (Cav1) is an essential component of caveolae whose Src kinase-dependent
phosphorylation on tyrosine 14 (Y14) is associated with regulation of focal adhesion dynamics. …

Gender differences in thyroid cancer: a critical review

R Yao, CG Chiu, SS Strugnell, S Gill… - Expert Review of …, 2011 - Taylor & Francis
It has long been known that the incidence of thyroid cancer in women is significantly higher
than that in men. The objective of this article is to review gender differences in thyroid cancer, …

Anaplastic thyroid cancer: a comprehensive review of novel therapy

SL Kojic, SS Strugnell, SM Wiseman - Expert Review of Anticancer …, 2011 - Taylor & Francis
Thyroid carcinomas are the most common cancer of the human endocrine system and are
typically classified as papillary, follicular, anaplastic or medullary carcinomas. Although …

[HTML][HTML] Hemithyroidectomy is the preferred initial operative approach for an indeterminate fine needle aspiration biopsy diagnosis

…, R Yao, SK Chan, SS Strugnell, S Bugis… - Canadian Journal of …, 2012 - ncbi.nlm.nih.gov
Background Fine needle aspiration biopsy represents the critical initial diagnostic test used
for evaluation of thyroid nodules. Our objectives were to determine the cytological distribution…

[HTML][HTML] Incremental value and clinical impact of neck sonography for primary hyperparathyroidism: a risk-adjusted analysis

…, V Nguyen, SS Strugnell, J Yang, S Jones… - Canadian Journal of …, 2013 - ncbi.nlm.nih.gov
Background Despite the different preoperative imaging modalities available for parathyroid
adenoma localization, there is currently no uniform consensus on the most appropriate …

Synoptic pathology reporting for thyroid cancer: a review and institutional experience

E Lam, N Vy, C Bajdik, SS Strugnell… - Expert Review of …, 2013 - Taylor & Francis
Thyroid cancer surgical pathology reports contain information that is critical for diagnosis,
determining completeness of resection, staging and guiding postoperative management. …

[HTML][HTML] Limited adequacy of thyroid cancer patient follow-up at a Canadian tertiary care centre

E Lam, SS Strugnell, C Bajdik, D Holmes… - Canadian Journal of …, 2013 - ncbi.nlm.nih.gov
Background We sought to evaluate the adequacy of follow-up of thyroid cancer patients at a
Canadian centre. Methods We mailed a survey to the family physicians of thyroid cancer …