[HTML][HTML] Prioritizing surgery during the COVID-19 pandemic: the Quebec guidelines

ME Bouthillier, M Lorange, S Legault… - Canadian Journal of …, 2021 - ncbi.nlm.nih.gov
In many countries, health care institutions have ramped down nonemergent activities in
order to free up hospital and critical care beds in anticipation of a wave of patients with …

Self-reported and objectively measured health indicators among a sample of Canadians living within the vicinity of industrial wind turbines: Social survey and sound …

…, N Broner, W Richarz, J Tsang, S Legault… - Noise News …, 2013 - ingentaconnect.com
In Canada, all levels of government share jurisdiction for regulating sound that could be
harmful to Canadians. The location of wind turbines and associated sound level limits fall under …

Synthesis and cytotoxicity of bidesmosidic betulin and betulinic acid saponins

C Gauthier, J Legault, S Lavoie… - Journal of natural …, 2009 - ACS Publications
The naturally occurring cytotoxic saponin 28-O-β-d-glucopyranosylbetulinic acid 3β-O-α-l-arabinopyranoside
(3) was easily synthesized along with seven bidesmosidic saponins …

Anticancer diarylheptanoid glycosides from the inner bark of Betula papyrifera

V Mshvildadze, J Legault, S Lavoie, C Gauthier… - Phytochemistry, 2007 - Elsevier
Phytochemical investigations of the MeOH extract of Betula papyrifera inner bark led to the
isolation of ten phenolic compounds of the following types: diarylheptanoid glycosides (1–4), …

Synthesis of two natural betulinic acid saponins containing α-l-rhamnopyranosyl-(1→ 2)-α-l-arabinopyranose and their analogues

C Gauthier, J Legault, S Lavoie, S Rondeau… - Tetrahedron, 2008 - Elsevier
A concise synthesis of naturally occurring betulinic acid saponins bearing an α-l-rhamnopyranosyl-(1→2)-α-l-arabinopyranoside
moiety at the C-3 position is described. Betulinic acid 3β…

[HTML][HTML] Cytotoxic Steroidal Saponins from the Flowers of Allium leucanthum

L Mskhiladze, J Legault, S Lavoie, V Mshvildadze… - Molecules, 2008 - mdpi.com
Allium leucanthum C. Koch is an endemic Caucasian species that grows in Georgia. The
flowers are used in traditional medicine. Phytochemical investigation allowed the isolation of …

Cytotoxic activity of withanolides isolated from Tunisian Datura metel L.

…, B Marzouk, V Mshvildadze, S Lavoie, J Legault - Phytochemistry, 2011 - Elsevier
Withanolide-type steroids, withametelin Q (1) and 12α-hydroxydaturametelin B (2) along with
three known withanolides, were isolated from leaves of Datura metel L. (Solanaceae). The …

A new labdane diterpene from the flowers of Solidago canadensis

ME Bradette-Hébert, J Legault, S Lavoie… - Chemical and …, 2008 - jstage.jst.go.jp
A new labdane diterpene, 9a, 16x-dihydroxy-6-oxo-7, 13-labdadien-15, 16-olide (solicanolide,
1) and six known compounds identified as quercetin (2), 3-O-caffeoylquinic acid (3, …

Isolation and identification of cytotoxic compounds from the wood of Pinus resinosa

F Simard, J Legault, S Lavoie… - Phytotherapy …, 2008 - Wiley Online Library
Methanol extracts of wood from Pinus resinosa were found to be selectively cytotoxic
against human lung carcinoma cells, A549 (IC 50 41 ± 6 µg/mL), human colorectal …

Terpenoids isolated from Tunisian Nigella sativa L. essential oil with antioxidant activity and the ability to inhibit nitric oxide production

…, S Lavoie, B Marzouk, J Legault - Flavour and …, 2012 - Wiley Online Library
Fractionation of the essential oil from the seeds of Nigella sativa (Ranunculaceae) led to the
isolation of four terpenoids: trans‐ (1), cis‐sabinene hydrate methyl ether (2), 1,2‐epoxy‐…