… In 1968 Dr Noonan published a case series with these 9 plus an additional 10 patients.
The eponym “Noonan syndrome” was adopted in recognition of Dr Noonan, because she was …

Noonan syndrome’is a rela-tively common multiple congenital anomaly syndrome, with an
esti-mated incidence of between one per 1,000 and one per 2,500 live births. 2 Affected …

Noonan syndrome is a genetic multisystem disorder characterised by distinctive facial features,
developmental delay, learning difficulties, short stature, congenital heart disease, renal …

Objective Noonan syndrome ( NS ) is the second most common genetic syndrome
associated with cardiac abnormalities, including, most notably, pulmonary stenosis ( PS ) and …

Short stature is a very common manifestation of Noonan syndrome (NS) and is accompanied
by a variable delay in bone age. Although reports of adult height in NS are uncommon, …

… Noonan-specific growth curves were designed in 1988 [9]. Growth hormone (GH) levels
are … Noonan syndrome is a heterogeneous but clinically recognisable, multiple congenital …

Noonan syndrome was first described over 20 years ago by Noonan and Ehmkel; they defined
a specific group of nine patients with valvular pulmonary stenosis who, in addition, had …

Clinical details are presented on 151 individuals with Noonan syndrome (83 males and 68
females, mean age 12.6 years). Polyhydramnios complicated 33% of affected pregnancies. …

After an introduction dealing with the “historical evolution” of the Noonan syndrome (NS),
we try to define the NS phenotype based on clinical descriptions published since 1883. The …

Noonan syndrome is a relatively common multiple malformation syndrome with characteristic
facies, short stature and congenital heart disease, most commonly pulmonary stenosis (…