Targeted delivery of drug molecules to organs or special sites is one of the most challenging
research areas in pharmaceutical sciences. By developing colloidal delivery systems such …

The purpose of this article is to review USP and non-pharmacopeial dissolution testing methods
for conventional and novel pharmaceutical dosage forms and give an insight to possible …

… Wilson Roa is a professor of oncology at the University of Alberta and a senior medical …
Roa contributes to scientific steering committees of research groups and consortiums, such …

Purpose The optimal radiotherapy regimen for elderly and/or frail patients with newly
diagnosed glioblastoma remains to be established. This study compared two radiotherapy …

Background Glioblastoma is associated with a poor prognosis in the elderly. Survival has
been shown to increase among patients 70 years of age or younger when temozolomide …

Glucose-capped gold nanoparticles (Glu-GNPs) have been used to improve cellular targeting
and radio-sensitization. In this study, we explored the mechanism of Glu-GNP enhanced …

Purpose To prospectively compare standard radiation therapy (RT) with an abbreviated
course of RT in older patients with glioblastoma multiforme (GBM). Patients and Methods One …

Purpose: This phase III randomized trial evaluated survival as well as neurologic and
neurocognitive function in patients with brain metastases from solid tumors receiving whole-brain …

PURPOSE: To evaluate prospectively the acute and late morbidities from a multiinstitutional
three-dimensional radiotherapy dose-escalation study for inoperable non–small-cell lung …

Purpose Previous trials have suggested a quality-of-life (QOL) improvement for anemic
cancer patients treated with erythropoietin, but few used QOL as the primary outcome. We …