SARS-CoV-2 in an Immunocompromised Host This letter describes an immunocompromised
patient who had persistent infection with SARS-CoV-2 over a period of months, despite …

Squamous metaplasia (SM) is common in smokers and is associated with airway
obstruction in chronic obstructive pulmonary disease (COPD). A major mechanism of airway …

Targeting virulence factors has gained increasing attention as a potential approach to new
antibiotics. Small molecule inhibitors of virulence have been shown to change the course of …

It is well understood that antigen-presenting cells (APCs) within tumors typically do not
maintain cytotoxic T cell (CTL) function, despite engaging them. Across multiple mouse tumor …

Shedding of Culturable SARS-CoV-2 with Omicron Outpatients with Covid-19 were followed
serially with frequent PCR and viral-culture assessments. The SARS-CoV-2 omicron (BA.1) …

Attending to a stimulus enhances its neuronal representation, even at the level of primary
sensory cortex. Cross-modal modulation can similarly enhance a neuronal representation, and …

Protein disulfide isomerases (PDIs) aid protein folding and assembly by catalyzing formation
and shuffling of cysteine disulfide bonds in the endoplasmic reticulum (ER). Many members …

Airway remodeling, caused by inflammation and fibrosis, is a major component of chronic
obstructive pulmonary disease (COPD) and currently has no effective treatment. Transforming …

The role of type I interferons (IFNs) in the host response to bacterial infections is
controversial. Here, we examined the role of IFN-α/β in the murine response to infection with …

Background Mild cognitive impairment (MCI) is a condition referring to the persons with
cognitive deficits measurable in some form or another, but not meeting criteria for dementia, and …