[HTML][HTML] Vaccine adjuvants: from 1920 to 2015 and beyond
A Di Pasquale, S Preiss, F Tavares Da Silva, N Garçon - Vaccines, 2015 - mdpi.com
The concept of stimulating the body’s immune response is the basis underlying vaccination.
Vaccines act by initiating the innate immune response and activating antigen presenting …
Vaccines act by initiating the innate immune response and activating antigen presenting …
Adjuvant system AS01: helping to overcome the challenges of modern vaccines
AM Didierlaurent, B Laupèze, A Di Pasquale… - Expert review of …, 2017 - Taylor & Francis
Introduction: Adjuvants are used to improve vaccine immunogenicity and efficacy by
enhancing antigen presentation to antigen-specific immune cells with the aim to confer long-term …
enhancing antigen presentation to antigen-specific immune cells with the aim to confer long-term …
Synthesis, luminescence properties, and explosives sensing with 1, 1-tetraphenylsilole-and 1, 1-silafluorene-vinylene polymers
JC Sanchez, AG DiPasquale, AL Rheingold… - Chemistry of …, 2007 - ACS Publications
The syntheses, spectroscopic characterizations, and fluorescence quenching efficiencies of
polymers and copolymers containing tetraphenylsilole- or silafluorene-vinylene repeat units …
polymers and copolymers containing tetraphenylsilole- or silafluorene-vinylene repeat units …
Concerted proton− electron transfer in the oxidation of hydrogen-bonded phenols
…, TF Markle, H Nagao, AG DiPasquale… - Journal of the …, 2006 - ACS Publications
Three phenols with pendant, hydrogen-bonded bases (HOAr-B) have been oxidized in
MeCN with various one-electron oxidants. The bases are a primary amine (−CPh 2 NH 2 ), an …
MeCN with various one-electron oxidants. The bases are a primary amine (−CPh 2 NH 2 ), an …
From discovery to licensure, the Adjuvant System story
N Garçon, A Di Pasquale - Human vaccines & immunotherapeutics, 2017 - Taylor & Francis
Adjuvants are substances added to vaccines to improve their immunogenicity. Used for
more than 80 years, aluminum, the first adjuvant in human vaccines, proved insufficient to …
more than 80 years, aluminum, the first adjuvant in human vaccines, proved insufficient to …
GDC-9545 (giredestrant): a potent and orally bioavailable selective estrogen receptor antagonist and degrader with an exceptional preclinical profile for ER+ breast …
…, JH Chang, S Daly, AG DiPasquale… - Journal of Medicinal …, 2021 - ACS Publications
Breast cancer remains a leading cause of cancer death in women, representing a significant
unmet medical need. Here, we disclose our discovery efforts culminating in a clinical …
unmet medical need. Here, we disclose our discovery efforts culminating in a clinical …
[HTML][HTML] Health care practitioners' responsibility to address intimate partner violence related to the COVID-19 pandemic
NL Bradley, AM DiPasquale, K Dillabough… - Cmaj, 2020 - Can Med Assoc
E610 CMAJ| JUNE 1, 2020| VOLUME 192| ISSUE 22 none exist currently. The EDUCATE
program (www. ipveducate. com/the-educate-training-program) is a multimodal training …
program (www. ipveducate. com/the-educate-training-program) is a multimodal training …
Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors
…, H Chen, X Ding, AG DiPasquale… - Journal of medicinal …, 2012 - ACS Publications
There is a high demand for potent, selective, and brain-penetrant small molecule inhibitors
of leucine-rich repeat kinase 2 (LRRK2) to test whether inhibition of LRRK2 kinase activity is …
of leucine-rich repeat kinase 2 (LRRK2) to test whether inhibition of LRRK2 kinase activity is …
Synthesis, structure, and magnetic properties of valence ambiguous dinuclear antiferromagnetically coupled cobalt and ferromagnetically coupled iron complexes …
KS Min, AG DiPasquale, JA Golen… - Journal of the …, 2007 - ACS Publications
Dinuclear [(TPyA)M II (CA 2 - )M II (TPyA)] 2+ [TPyA = tris(2-pyridylmethyl)amine; CA 2 - =
chloranilate dianion; M = Co (1 2+ ), Fe (2 2+ )] complexes have been prepared by the reaction …
chloranilate dianion; M = Co (1 2+ ), Fe (2 2+ )] complexes have been prepared by the reaction …
Probing concerted proton–electron transfer in phenol–imidazoles
A series of seven substituted 4,6-di-tert-butyl-2-(4,5-diarylimidazolyl)-phenols have been
prepared and characterized, along with two related benzimidazole compounds. X-ray crystal …
prepared and characterized, along with two related benzimidazole compounds. X-ray crystal …