Background: Fluid resuscitation is the cornerstone of sepsis treatment. However, whether
balanced or unbalanced crystalloids or natural or synthetic colloids confer a survival …

Background Restricted visitation policies in acute care settings because of the COVID-19
pandemic have negative consequences. The objective of this scoping review is to identify …

Materials and methods: MEDLINE and EMBASE were searched from inception to July 2012
for RCTs using a Lactobacillus prophylactic against rUTI in premenopausal adult women. A …

Introduction Although sepsis is the leading cause of death in noncoronary critically ill
patients, identification of patients at high risk of death remains a challenge. In this study, we …

Objective: To determine the utility of angiopoietin-1 and angiopoietin-2 as potentially novel
biomarkers of morbidity and mortality in patients with severe sepsis. Design: Multicenter …

Objectives— Sepsis is characterized by systemic activation of inflammation and coagulation
in response to infection. In sepsis, activated neutrophils extrude neutrophil extracellular …

The accuracy of the signs and tests that clinicians use to diagnose ventilator-associated
pneumonia (VAP) and initiate antibiotic treatment has not been well characterized. We sought to …

Purpose In shock, hypotension may contribute to inadequate oxygen delivery, organ failure
and death. We conducted the Optimal Vasopressor Titration (OVATION) pilot trial to inform …

AKI after cardiac surgery remains strongly associated with mortality and lacks effective
treatment or prevention. Preclinical studies suggest that cell-based interventions may influence …

Inhaled nitric oxide (NO) is being used more and more in intensive care units as a modality
to improve the outcome of patients with pulmonary complications. Our objective was to …