Temozolomide is the most widely used chemotherapy for patients with glioblastoma (GBM)
despite the fact that approximately half of treated patients have temozolomide resistance and …

Chimeric antigen receptor (CAR) T-cell therapy targeting solid tumors has stagnated as a
result of tumor heterogeneity, immunosuppressive microenvironments, and inadequate …

Controversy surrounds the role of cytomegalovirus (CMV) in glioblastoma (GBM). However,
several studies have shown that CMV nucleic acids and proteins are present within GBM …

… as the only port of Pakistan, Karachi has an undisputed place in the … Karachi is a new city
but it is old in its wisdom and tolerance. … It is this mainstream Karachi that this book is about. …

Immunotherapy has revolutionized care for many solid tissue malignancies, and is being
investigated for efficacy in the treatment of malignant brain tumors. Identifying a non-invasive …

Resistance to VEGF therapy in glioblastoma is driven by upregulation of Tregs, combined
blockade of VEGF, and Tregs may provide an additive antitumor effect for treating glioblastoma…

Background The changes induced in host immunity and the tumor microenvironment by
chemotherapy have been shown to impact immunotherapy response in both a positive and a …

Background: Malignant gliomas are heterogeneous brain tumors with the potential for aggressive
disease progression, as influenced by suppressive immunoediting. Given the success …

Translation of nanoparticles (NPs) into human clinical trials for patients with refractory cancers
has lagged due to unknown biologic reactivities of novel NP designs. To overcome these …

The aim of this study was ultrasound assisted removal of Ceftriaxone sodium (CS) based on
CCD model. Using sonochemical synthesized Bi 2 WO 6 implanted on graphitic carbon …