User profiles for A. Morokoff

A/Prof Andrew Morokoff

Neurosurgeon, University of Melbourne, Royal Melbourne Hospital
Verified email at unimelb.edu.au
Cited by 3714

The emergent role of exosomes in glioma

J Gourlay, AP Morokoff, RB Luwor, HJ Zhu… - Journal of Clinical …, 2017 - Elsevier
Extracellular vesicles (EVs) are known mediators of intercellular communication for both
normal and tumour cells. With the capability to transfer nucleic acids, proteins and lipids, EVs …

[HTML][HTML] The role of interleukin‑6‑STAT3 signalling in glioblastoma

…, SS Stylli, H Nguyen, AP Morokoff… - Oncology …, 2018 - spandidos-publications.com
Glioblastoma is the most common type of malignant brain tumor among adults and is
currently a non‑curable disease due primarily to its highly invasive phenotype, and the lack of …

[PDF][PDF] The role of spinal surgery in the treatment of low back pain

L Evans, T O'Donohoe, A Morokoff… - The Medical Journal of …, 2023 - mja.com.au
• Low back pain (LBP) is common and a leading cause of disability and lost productivity
worldwide. • Acute LBP is frequently self-resolving, but recurrence is common, and a significant …

[HTML][HTML] Motor neuroprosthesis implanted with neurointerventional surgery improves capacity for activities of daily living tasks in severe paralysis: first in-human …

…, V Hampshire, RP Sharma, A Morokoff… - Journal of …, 2021 - jnis.bmj.com
Background Implantable brain–computer interfaces (BCIs), functioning as motor neuroprostheses,
have the potential to restore voluntary motor impulses to control digital devices and …

Prediction of seizure likelihood with a long-term, implanted seizure advisory system in patients with drug-resistant epilepsy: a first-in-man study

…, TJ O'Brien, SF Berkovic, M Murphy, A Morokoff… - The Lancet …, 2013 - thelancet.com
Background Seizure prediction would be clinically useful in patients with epilepsy and could
improve safety, increase independence, and allow acute treatment. We did a multicentre …

[HTML][HTML] Expression of CD133 and CD44 in glioblastoma stem cells correlates with cell proliferation, phenotype stability and intra-tumor heterogeneity

…, S Amiridis, N Kountouri, W Ng, AP Morokoff… - PLoS …, 2017 - journals.plos.org
Glioblastoma (GBM) is a heterogeneous tumor of the brain with a poor prognosis due to
recurrence and drug resistance following therapy. Genome-wide profiling has revealed the …

[HTML][HTML] VDAC2 enables BAX to mediate apoptosis and limit tumor development

…, S Chappaz, SL Khaw, C Chang, A Morokoff… - Nature …, 2018 - nature.com
Intrinsic apoptosis is critical to prevent tumor formation and is engaged by many anti-cancer
agents to eliminate tumor cells. BAX and BAK, the two essential mediators of apoptosis, are …

Surgery for convexity meningiomas

AP Morokoff, J Zauberman, PM Black - Neurosurgery, 2008 - journals.lww.com
OBJECTIVE: Meningiomas that occur over the convexity of the brain are the most common
meningiomas, but little has been published about their contemporary management. We …

[HTML][HTML] Coexpression analysis of CD133 and CD44 identifies proneural and mesenchymal subtypes of glioblastoma multiforme

…, MD Giovanna, A Gogos, W Ng, AP Morokoff… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Accumulating evidence suggests that the stem cell markers CD133 and CD44 indicate molecular
subtype in Glioblastoma Multiforme (GBM). Gene coexpression analysis of The Cancer …

IDH1 mutation is associated with seizures and protoplasmic subtype in patients with low‐grade gliomas

…, KJ Drummond, TJ O'Brien, AH Kaye, AP Morokoff - …, 2014 - Wiley Online Library
Objective The isocitrate dehydrogenase 1 ( IDH 1) R132H mutation is the most common
mutation in World Health Organization ( WHO) grade II gliomas, reported to be expressed in 70–…