Background Current stabilization methods for periprosthetic fractures of the distal femur are
inadequate in achieving fracture fixation, with complication rates as high as 29%. A major …

Background and Purpose—In clinical trials and observational studies there is considerable
inconsistency in the use of definitions to describe delayed cerebral ischemia (DCI) after …

OBJECTIVE: Incisional cerebrospinal fluid (CSF) leakage after cranial surgery is a
significant cause of morbidity due to poor wound healing and infection, meningitis, and …

✓ There is still controversy over whether or not patients should be hyperventilated after
traumatic brain injury, and a randomized trial has never been conducted. The theoretical …

Background CT imaging of head-injured children has risks of radiation-induced malignancy.
Our aim was to identify children at very low risk of clinically-important traumatic brain …

Background Traumatic brain injury is a major cause of death and disability. We sought to
assess the safety and efficacy of dexanabinol, a synthetic cannabinoid analogue devoid of …

✓ Formation of the oxygen radical superoxide anion is one of the final events of several
metabolic pathways in the cascade that leads to delayed neuronal death after traumatic or …

Acute secondary adrenal insufficiency after traumatic brain... : Critical Care Medicine Acute
secondary adrenal insufficiency after traumatic brain injury: A prospective study* : Critical …

Background and Purpose— Cerebral vasospasm continues to be a major cause of poor
outcome in patients with ruptured aneurysms. Prophylactic Transluminal Balloon Angioplasty (…

Background On the basis of mixed results from previous trials, we assessed whether therapeutic
hypothermia for 48–72 h with slow rewarming improved mortality in children after brain …