Visualized data often have dubious origins and quality. Di erent forms of uncertainty and errors
are also introduced as the data are derived, transformed, interpolated, and nally rendered…

SARS-CoV-2 is a newly identified member of the coronavirus family that has caused the
Coronavirus disease 2019 (COVID-19) pandemic. This rapidly evolving and unrelenting SARS-…

Presented here is a genome sequence of an individual human. It was produced from ∼32
million random DNA fragments, sequenced by Sanger dideoxy technology and assembled …

Structural variations of DNA greater than 1 kilobase in size account for most bases that vary
among human genomes, but are still relatively under-ascertained. Here we use tiling …

Evaluation of calcification in breast lesions is a major assessment criterion for breast
mammography. The morphology and distribution of the calcification are related to the histology of …

The incomplete identification of structural variants (SVs) from whole-genome sequencing
data limits studies of human genetic diversity and disease association. Here, we apply a suite …

From the standpoint of supporting human-centered discovery of knowledge, the present-day
model of mining association rules suffers from the following serious shortcomings: (i) lack of …

Cancer immunotherapies provide survival benefits in responding patients, but many patients
fail to respond. Identifying the biology of treatment response and resistance are a priority to …

We present the first comprehensive analysis of a diploid human genome that combines
single-molecule sequencing with single-molecule genome maps. Our hybrid assembly markedly …

Salamanders serve as important tetrapod models for developmental, regeneration and
evolutionary studies. An extensive molecular toolkit makes the Mexican axolotl (Ambystoma …