[HTML][HTML] Comparative analysis of exosome isolation methods using culture supernatant for optimum yield, purity and downstream applications
Exosomes have received significant attention for their role in pathobiological processes and
are being explored as a tool for disease diagnosis and management. Consequently, various …
are being explored as a tool for disease diagnosis and management. Consequently, various …
[HTML][HTML] Mitochondrial fusion and fission: The fine-tune balance for cellular homeostasis
Mitochondria are highly dynamic, maternally inherited cytoplasmic organelles, which fulfill
cellular energy demand through the oxidative phosphorylation system. Besides, they play an …
cellular energy demand through the oxidative phosphorylation system. Besides, they play an …
Inhibitory effects of cranberry polyphenols on formation and acidogenicity of Streptococcus mutans biofilms
Cranberry fruit is a rich source of polyphenols, and has shown biological activities against
Streptococcus mutans. In the present study, we examined the influence of extracts of flavonols …
Streptococcus mutans. In the present study, we examined the influence of extracts of flavonols …
Inhibition of MUC4 Expression Suppresses Pancreatic Tumor Cell Growth and Metastasis
The MUC4 mucin is a high molecular weight membrane-bound glycoprotein. It is aberrantly
expressed in pancreatic tumors and tumor cell lines with no detectable expression in the …
expressed in pancreatic tumors and tumor cell lines with no detectable expression in the …
[HTML][HTML] Structure, evolution, and biology of the MUC4 mucin
Mucins are high-molecular-weight glycoproteins and are implicated in diverse biological
functions. MUC4, a member of transmembrane mucin family, is expressed in airway epithelial …
functions. MUC4, a member of transmembrane mucin family, is expressed in airway epithelial …
[HTML][HTML] Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine …
…, MC Patton, S Singh, M Khushman, AP Singh - British journal of …, 2017 - nature.com
Background: Chemoresistance is a significant clinical problem in pancreatic cancer (PC)
and underlying molecular mechanisms still remain to be completely understood. Here we …
and underlying molecular mechanisms still remain to be completely understood. Here we …
Polyphenols content and antioxidant capacity of eggplant pulp
The influence of organic and conventional farming practices on the phenolic content in
eggplant samples belonging to two cultivars, Blackbell (American eggplant) and Millionaire (…
eggplant samples belonging to two cultivars, Blackbell (American eggplant) and Millionaire (…
Honokiol: a novel natural agent for cancer prevention and therapy
Honokiol (3',5-di-(2-propenyl)-1,1'-biphenyl-2,4'-diol) is a bioactive natural product derived
from Magnolia spp. Recent studies have demonstrated anti-inflammatory, anti-angiogenic, …
from Magnolia spp. Recent studies have demonstrated anti-inflammatory, anti-angiogenic, …
MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells
SK Srivastava, A Bhardwaj, S Singh, S Arora… - …, 2011 - academic.oup.com
Pancreatic cancer (PC) has the worst prognosis among all cancers due to its late diagnosis
and lack of effective therapies. Therefore, identification of novel gene targets, which are …
and lack of effective therapies. Therefore, identification of novel gene targets, which are …
[HTML][HTML] An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor …
S Arora, A Bhardwaj, S Singh, SK Srivastava… - Journal of Biological …, 2013 - ASBMB
Recently, we have shown that CXCL12/CXCR4 signaling plays an important role in gemcitabine
resistance of pancreatic cancer (PC) cells. Here, we explored the effect of gemcitabine …
resistance of pancreatic cancer (PC) cells. Here, we explored the effect of gemcitabine …