[HTML][HTML] Causal relationship between the loss of RUNX3 expression and gastric cancer

…, T Ikeda, S Itohara, J Inazawa, T Abe, A Hagiwara… - Cell, 2002 - cell.com
Runx3/Pebp2αC null mouse gastric mucosa exhibits hyperplasias due to stimulated
proliferation and suppressed apoptosis in epithelial cells, and the cells are resistant to growth-…

Milky spots as the implantation site for malignant cells in peritoneal dissemination in mice

A Hagiwara, T Takahashi, K Sawai, H Taniguchi… - Cancer research, 1993 - AACR
We examined the site-specific implantation of cancer cells in peritoneal tissues after an ip
inoculation of 10 5 P388 leukemia cells. Twenty-four h after the inoculation, the number of …

Amplification and over‐expression of the AIB1 nuclear receptor co‐activator gene in primary gastric cancers

C Sakakura, A Hagiwara, R Yasuoka… - … journal of cancer, 2000 - Wiley Online Library
Our analysis of chromosomal aberrations in primary gastric cancers using comparative genomic
hybridization has revealed novel, high and frequent copy number increases in the long …

[HTML][HTML] Intrathoracic esophageal replacement by in situ tissue-engineered esophagus

…, J Hamuro, Y Ikada, E Otsuji, A Hagiwara - The Journal of Thoracic …, 2008 - Elsevier
OBJECTIVE: This study aimed to evaluate in situ tissue-engineered esophagus in a canine
model after experimental resection and replacement of a full circumferential defect of the …

Possible involvement of inositol 1, 4, 5-trisphosphate receptor type 3 (IP3R3) in the peritoneal dissemination of gastric cancers.

C Sakakura, A Hagiwara, K Fukuda… - Anticancer …, 2003 - europepmc.org
Our previous study using cDNA microarray showed that differentially expressed genes
among gastric cancer cells involved in peritoneal dissemination could be positively identified. …

Gains, losses, and amplifications of genomic materials in primary gastric cancers analyzed by comparative genomic hybridization

…, T Shinomiya, K Date, A Hagiwara… - Genes …, 1999 - Wiley Online Library
By means of comparative genomic hybridization (CGH), we screened 58 primary gastric
cancers for changes in copy number of DNA sequences. We detected frequent losses on 1p32–…

Prophylaxis with carbon-adsorbed mitomycin against peritoneal recurrence of gastric cancer

A Hagiwara, T Takahashi, O Kojima, K Sawai… - The Lancet, 1992 - Elsevier
Attempts to prevent peritoneal carcinomatosis after surgery for gastric cancer by intraperitoneal
administration of anticancer drugs have not been successful, largely because the drugs …

Dendritic cell-based immunotherapy of cancer with carcinoembryonic antigen-derived, HLA-A24-restricted CTL epitope: Clinical outcomes of 18 patients with …

…, H Itoi, T Sonoyama, A Hagiwara… - International …, 2004 - spandidos-publications.com
We conducted a clinical study of cancer vaccine therapy with dendritic cells (DCs) and HLA-A24-restricted
carcinoembryonic antigen (CEA)-derived peptide to assess the feasibility and …

Analysis of lymph node metastasis in early gastric cancer: rationale of limited surgery

…, T Yamaguchi, H Taniguchi, A Hagiwara… - Journal of surgical …, 1997 - Wiley Online Library
Background Since the majority of patients with early gastric cancer show long‐term survival
after surgery, a special attention must be directed to preserving gastric function in these …

Overexpression of bax sensitizes human breast cancer MCF‐7 cells to radiation‐induced apoptosis

…, T Ohyama, J Yamazaki, A Hagiwara… - … journal of cancer, 1996 - Wiley Online Library
Resistance to apoptosis plays an important role in tumors that are refractory to chemotherapy
and ionizing radiation (IR). bax, which forms a heterodimer with bcl‐2 and accelerates …