Gene delivery to the spinal cord using MRI-guided focused ultrasound

…, A Burgess, J Finkelstein, AJM Yee… - Gene therapy, 2015 - nature.com
Non-invasive gene delivery across the blood–spinal cord barrier (BSCB) remains a challenge
for treatment of spinal cord injury and disease. Here, we demonstrate the use of magnetic …

Intraoperative ultrasound in spine decompression surgery: a systematic review

J Tat, J Tat, S Yoon, AJM Yee, J Larouche - Spine, 2022 - journals.lww.com
Study Design. Systematic review. Objective. The aim of this study was to review the current
spine surgery literature to establish a definition for adequate spine decompression using …

[HTML][HTML] The effect of versican G3 domain on local breast cancer invasiveness and bony metastasis

AJM Yee, M Akens, BL Yang, J Finkelstein… - Breast Cancer …, 2007 - Springer
Introduction Increased versican expression has been associated with local breast cancer
invasiveness and a more aggressive tumor phenotype. The cellular mechanisms are not fully …

A novel thiol-modified hyaluronan and elastin-like polypetide composite material for tissue engineering of the nucleus pulposus of the intervertebral disc

…, L Gordon, KA Woodhouse, CM Whyne, AJM Yee - Spine, 2011 - journals.lww.com
Study Design. Biomechanical, in vitro, and initial in vivo evaluation of a thiol-modified hyaluronan
(TM-HA) and elastin-like polypeptide (ELP) composite hydrogel for nucleus pulposus (…

A randomized trial of hydroxyapatite coated prostheses in total hip arthroplasty

AJM Yee, HK Kreder, I Bookman… - … and Related Research®, 1999 - journals.lww.com
In a prospective randomized trial, 62 consecutive primary cementless total hip arthroplasties
in 55 patients were performed by one surgeon using either hydroxyapatite coated (35 hips) …

[HTML][HTML] The who, what and when of surgery for the degenerative lumbar spine: a population-based study of surgeon factors, surgical procedures, recent trends and …

…, JA Finkelstein, MH Ford, AJM Yee - Canadian Journal of …, 2009 - ncbi.nlm.nih.gov
Background Degenerative disease of the lumbar spine (DLS) is a common condition for
which surgery can be beneficial in selected patients. With recent surgical trends toward more …

Closure of the annulus fibrosus of the intervertebral disc using a novel suture application device—in vivo porcine and ex vivo biomechanical evaluation

…, AHW Chan, RD Harrison, W Oakden, AJM Yee… - The Spine Journal, 2016 - Elsevier
Background Context Defects in the annulus fibrosus (AF) remain a challenge in the surgical
treatment of lumbar disc herniations with persistent defects, allowing potential re herniation …

Volume of lytic vertebral body metastatic disease quantified using computed tomography–based image segmentation predicts fracture risk after spine stereotactic …

…, H Soliman, YK Lee, H Ebrahimi, AJM Yee… - International Journal of …, 2017 - Elsevier
Purpose To determine a threshold of vertebral body (VB) osteolytic or osteoblastic tumor
involvement that would predict vertebral compression fracture (VCF) risk after stereotactic body …

Defining the therapeutic window of vertebral photodynamic therapy in a murine pre-clinical model of breast cancer metastasis using the photosensitizer BPD-MA …

…, J Schwock, CM Whyne, S Burch, AJM Yee - Breast cancer research …, 2010 - Springer
Breast cancer is known to cause metastatic lesions in the bone, which can lead to skeletal-related
events. Currently, radiation therapy and surgery are the treatment of choice, but the …

Beyond bisphosphonates: photodynamic therapy structurally augments metastatically involved vertebrae and destroys tumor tissue

…, MK Akens, S Burch, AJM Yee… - Breast cancer research …, 2010 - Springer
Breast cancer patients commonly develop metastases in the spine, which compromises its
mechanical stability and can lead to skeletal related events. The current clinical standard of …