Following an initial impact after spinal cord injury (SCI), there is a cascade of downstream
events termed 'secondary injury', which culminate in progressive degenerative events in the …

AMPA receptors (AMPARs) are not thought to be involved in the induction of long-term
potentiation (LTP), but may be involved in its expression via second messenger pathways. …

Neuropathic pain is a common and often incapacitating clinical problem for which little useful
therapy is presently available. Painful peripheral neuropathies can have many etiologies, …

Purpose: In this study, we assessed the effects of topiramate (TPM) on high‐voltage‐activated
calcium channel (HVACC) currents in vitro. Methods: HVACC currents were recorded from …

Gap junctions are cytoplasmic channels connecting adjacent cells and mediating their
electrical and metabolic coupling. Different cell types in the CNS express various gap junction …

Axonal dysfunction after spinal cord injury (SCI) and other types of neurotrauma is associated
with demyelination and exposure of juxtaparanodal K + channels. In this study, sucrose …

The compactness of myelin allows for efficient insulation defining rapid propagation of action
potentials, but also raises questions about how cytoplasmic access to its membranes is …

J. Neurochem. (2010) 113, 826–835. Abstract The ketogenic diet (KD), used successfully to
treat a variety of epilepsy syndromes in humans and to attenuate seizures in different animal …

1 The whole‐cell recording technique, combined with internal perfusion, was used to study
the effects of intracellular Ca 2+ buffering on fast, medium and slow after‐hyperpolarizations (…

Background Cell reprogramming is a promising avenue for cell-based therapies as it allows
for the generation of multipotent, unipotent, or mature somatic cells without going through a …