Background. Despite the various immunosuppressive regimens presently in use, acute
rejection in the early postoperative period continues to occur in 20 to 40% of renal transplant …

We randomly assigned 71 patients with active chronic Crohn's disease who were resistant
to or intolerant of corticosteroids to treatment with oral cyclosporine (5 to 7.5 mg per kilogram …

Summary A series of 32 recipients of liver, kidney, or pancreas transplants who were treated
with sirolimus and low-dose tacrolimus experienced a low rate of rejection and excellent …

Background. Whether routine ureteric stenting in low-urological-risk patients reduces the risk
of urological complications in kidney transplantation is not established. Methods. Eligible …

Patients with chronic renal failure (CRF) are at increased risk for pathological calcifications
because of increased serum calcium-phosphorus products. A minority, including those …

Although sirolimus (SRL) binds the immunophilin FK506‐binding protein‐12 (FKBP‐12)
with greater avidity than tacrolimus (TAC), animal studies have shown that SRL and TAC act …

THE INCIDENCE AND IMPACT OF EARLY REJECTION EPISODES ON GRAF... :
Transplantation THE INCIDENCE AND IMPACT OF EARLY REJECTION EPISODES ON …

The pharmacokinetic (PK) interaction between tacrolimus (TAC) and sirolimus (SRL), similarly
structured immunosuppressive compounds that share binding proteins, is unknown. The …

Background. The aim of thisstudy is to evaluate the effects of RAPA conversion in patients
undergoing cyclosporine (CsA) or tacrolimus (Tac) toxicity. Methods. Twenty renal transplant …

Patients with limited stage small cell lung cancer were initially randomized to receive either
three courses of Cyclophosphamide, Adriamycin, and Vincristine (CAV) followed by three …