High-throughput behavioral analysis in C. elegans
We designed a real-time computer vision system, the Multi-Worm Tracker (MWT), which can
simultaneously quantify the behavior of dozens of Caenorhabditis elegans on a Petri plate …
simultaneously quantify the behavior of dozens of Caenorhabditis elegans on a Petri plate …
Young children's theory of mind and emotion
PL Harris, CN Johnson, D Hutton, G Andrews… - Cognition & …, 1989 - Taylor & Francis
In three experiments, children aged 3 to 7 years were tested for their understanding of the
impact of beliefs and desires on emotion. Children watched while animal characters were …
impact of beliefs and desires on emotion. Children watched while animal characters were …
[PDF][PDF] Dopamine mediates context-dependent modulation of sensory plasticity in C. elegans
Dopamine has been implicated in the modulation of diverse forms of behavioral plasticity,
including appetitive learning and addiction. An important challenge is to understand how …
including appetitive learning and addiction. An important challenge is to understand how …
The use of a temporal analogue to investigate the possible impact of projected global warming on the UK tourist industry
AR Giles, AH Perry - Tourism management, 1998 - Elsevier
Tourism in the UK benefited from the continued ‘hot spell’ throughout the three summer
months in 1995. A revival of the traditional British seaside holiday was experienced whilst …
months in 1995. A revival of the traditional British seaside holiday was experienced whilst …
Behavioral and genetic characterization of habituation using Caenorhabditis elegans
This review surveys the literature that investigates the behavioral characterization and
cellular and molecular mechanisms of habituation using the model organism Caenorhabditis …
cellular and molecular mechanisms of habituation using the model organism Caenorhabditis …
Effect of colchicine on perioperative atrial fibrillation and myocardial injury after non-cardiac surgery in patients undergoing major thoracic surgery (COP-AF): an …
Background Higher levels of inflammatory biomarkers are associated with an increased risk
of perioperative atrial fibrillation and myocardial injury after non-cardiac surgery (MINS). …
of perioperative atrial fibrillation and myocardial injury after non-cardiac surgery (MINS). …
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking
Repeated exposure to opioids causes tolerance, which limits their analgesic utility and
contributes to overdose and abuse liability. However, the molecular mechanisms underpinning …
contributes to overdose and abuse liability. However, the molecular mechanisms underpinning …
Genetic behavioral screen identifies an orphan anti-opioid system
Opioids target the μ-opioid receptor (MOR) to produce unrivaled pain management, but their
addictive properties can lead to severe abuse. We developed a whole-animal behavioral …
addictive properties can lead to severe abuse. We developed a whole-animal behavioral …
Genetic modeling of GNAO1 disorder delineates mechanisms of Gαo dysfunction
D Wang, M Dao, BS Muntean, AC Giles… - Human Molecular …, 2022 - academic.oup.com
GNAO1 encephalopathy is a neurodevelopmental disorder with a spectrum of symptoms that
include dystonic movements, seizures and developmental delay. While numerous GNAO1 …
include dystonic movements, seizures and developmental delay. While numerous GNAO1 …
Context-dependent operation of neural circuits underlies a navigation behavior in Caenorhabditis elegans
The nervous system evaluates environmental cues and adjusts motor output to ensure
navigation toward a preferred environment. The nematode Caenorhabditis elegans navigates in …
navigation toward a preferred environment. The nematode Caenorhabditis elegans navigates in …