Type IV pili: dynamics, biophysics and functional consequences
The surfaces of many bacteria are decorated with long, exquisitely thin appendages called
type IV pili (T4P), dynamic filaments that are rapidly polymerized and depolymerized from a …
type IV pili (T4P), dynamic filaments that are rapidly polymerized and depolymerized from a …
Incidence and predictors of early recanalization after intravenous thrombolysis: a systematic review and meta-analysis
Background and Purpose— After the demonstration of efficacy of bridging therapy, reliably
predicting early recanalization (ER; ≤3 hours after start of intravenous thrombolysis) would …
predicting early recanalization (ER; ≤3 hours after start of intravenous thrombolysis) would …
How bacteria use type IV pili machinery on surfaces
The bacterial type IV pilus (T4P) is a versatile molecular machine with a broad range of
functions. Recent advances revealed that the molecular components and the biophysical …
functions. Recent advances revealed that the molecular components and the biophysical …
Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells
Macrophages have a key role in shaping the tumour microenvironment (TME), tumour
immunity and response to immunotherapy, which makes them an important target for cancer …
immunity and response to immunotherapy, which makes them an important target for cancer …
Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
The human kidney contains up to 2 million epithelial nephrons responsible for blood filtration.
Regenerating the kidney requires the induction of the more than 20 distinct cell types …
Regenerating the kidney requires the induction of the more than 20 distinct cell types …
A conserved dendritic-cell regulatory program limits antitumour immunity
Checkpoint blockade therapies have improved cancer treatment, but such immunotherapy
regimens fail in a large subset of patients. Conventional type 1 dendritic cells (DC1s) control …
regimens fail in a large subset of patients. Conventional type 1 dendritic cells (DC1s) control …
Students' expectations of, and experiences in e-learning: Their relation to learning achievements and course satisfaction
M Paechter, B Maier, D Macher - Computers & education, 2010 - Elsevier
… In part b, they evaluated statements describing positive or negative learning experiences
on a six-point scale (ranging from 1 “I disagree completely” to 6 “I agree completely”). In part c, …
on a six-point scale (ranging from 1 “I disagree completely” to 6 “I agree completely”). In part c, …
Effective containment explains subexponential growth in recent confirmed COVID-19 cases in China
BF Maier, D Brockmann - Science, 2020 - science.org
… In data from China collected in February 2020, Maier and Brockmann noticed that,
unexpectedly, the epidemic did not take off exponentially. Nonexponential spread occurs when the …
unexpectedly, the epidemic did not take off exponentially. Nonexponential spread occurs when the …
A circadian clock in macrophages controls inflammatory immune responses
Time of day-dependent variations of immune system parameters are ubiquitous phenomena
in immunology. The circadian clock has been attributed with coordinating these variations …
in immunology. The circadian clock has been attributed with coordinating these variations …
Modulation of mammalian life span by the short isoform of p53
B Maier, W Gluba, B Bernier, T Turner… - Genes & …, 2004 - genesdev.cshlp.org
Overexpression of the short isoform of p53 (p44) has unexpectedly uncovered a role for p53
in the regulation of size and life span in the mouse. Hyperactivation of the insulin-like growth …
in the regulation of size and life span in the mouse. Hyperactivation of the insulin-like growth …