… It was demonstrated that tumour-infiltrating B cells harvested from patients can present … B
cells were associated with activated IFNγ + CD4 + T cells, and exhausted tumour-infiltrating B …

… anthracis edema and lethal toxins initially involves specific, receptor-mediated binding of
“B… , the “B” oligomers are generated only after proteolysis of “B” precursor molecules. The “B” …

Phosphatase and Tensin Homolog deleted on Chromosome 10 (PTEN) is a dual phosphatase
with both protein and lipid phosphatase activities. PTEN was first discovered as a tumor …

The surface of Saturn’s haze-shrouded moon Titan has long been proposed to have oceans
or lakes, on the basis of the stability of liquid methane at the surface 1 , 2 . Initial visible 3 …

… (B) S6 kinase activity was measured by in vitro kinase assay (31) in MDCK cells stably
transfected with vector or wild-type PTEN (Left) and in LAPC-4 prostate cancer cells stably …

… Notwithstanding a phase II trial conducted by the Cancer and Leukemia Group B (CALGB
39802) demonstrating the safety and feasibility of lobectomy, 19 the acceptance of VATS …

Background Previous phase 2 trials of neoadjuvant anti-PD-1 or anti-PD-L1 monotherapy in
patients with early-stage non-small-cell lung cancer have reported major pathological …

The most recent Cassini RADAR images of Titan show widespread regions (up to 1500
kilometers by 200 kilometers) of near-parallel radar-dark linear features that appear to be seas of …

… (B) Histological analysis of liver sections from WT and mutant mice. (Top) Hematoxylin/eosin
staining. (Middle) Periodic acid Schiff's staining (Bottom) Oil red O staining. …

… 3B, arrow). Acini in early stages of the transition exhibited localized expansion of small cells,
continuous with an enlarged acinar lumen (Figure 3B, … Figure 4B), recombination in other …