Context Chronic hepatitis C virus (HCV) infection outcomes include liver failure, hepatocellular
carcinoma (HCC), and liver-related death. Objective To assess the association between …

Background: Clinical outcomes of chronic hepatitis C infection in patients with advanced
fibrosis include liver failure, hepatocellular carcinoma, and death. Objective: To investigate …

BACKGROUND & AIMS: Therapy with pegylated interferon (PEG-IFN)–alfa results in sustained
response in a minority of patients with chronic hepatitis B virus (HBV) infection and has …

BACKGROUND & AIMS: Ursodeoxycholic acid (UDCA) improves laboratory liver test results
in patients with primary biliary cirrhosis (PBC). Few studies have assessed the prognostic …

Background & Aims: The aim of this study was to evaluate the long-term sustainability of
response in patients with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B treated with …

In the treatment of chronic hepatitis B (CHB), the ultimate goal is preventing hepatitis B virus
(HBV)-associated liver disease, including hepatocellular carcinoma (HCC). Recently …

Background & Aims Noninvasive surrogate end points of long-term outcomes of patients
with primary biliary cirrhosis (PBC) are needed to monitor disease progression and evaluate …

Background & Aims Primary sclerosing cholangitis (PSC) is an orphan hepatobiliary
disorder associated with inflammatory bowel disease (IBD). We aimed to estimate the risk of …

Data on the long‐term effects of interferon alfa (IFN) treatment on disease progression and
mortality in patients with chronic hepatitis B (CHB) are limited. To evaluate factors that …

Serum hepatitis B surface antigen (HBsAg) levels may reflect the immunomodulatory efficacy
of pegylated interferon (PEG‐IFN). We investigated within a large randomized trial whether …