AMPK has emerged as a critical mechanism for salutary effects of polyphenols on lipid metabolic
disorders in type 1 and type 2 diabetes. Here we demonstrate that AMPK interacts with …

With trauma, sepsis, cancer, or uremia, animals or patients experience accelerated degradation
of muscle protein in the ATP-ubiquitin-proteasome (Ub-P’some) system. The initial step …

Parkinson’s disease affects 5 million people worldwide, but the molecular mechanisms
underlying its pathogenesis are still unclear. Here, we report a genome-wide meta-analysis of …

SARS-CoV-2 has been spreading around the world for the past year. Recently, several variants
such as B. 1.1. 7 (alpha), B. 1.351 (beta), and P. 1 (gamma), which share a key mutation …

Regulator of G protein signaling (RGS) proteins are responsible for the rapid turnoff of G
protein–coupled receptor signaling pathways. The major mechanism whereby RGS proteins …

Deep learning has received extensive research interest in developing new medical image
processing algorithms, and deep learning based models have been remarkably successful in …

Dysregulation of autophagy, a cellular catabolic mechanism essential for degradation of
misfolded proteins, has been implicated in multiple neurodegenerative diseases. However, the …

Thioredoxin-interacting protein (TXNIP) is an α-arrestin family protein that is induced in response
to glucose elevation. It has been shown to provide a negative feedback loop to regulate …

… Morteza Heidari and Bin Zheng design the study. Morteza Heidari implements the idea and
write the required computer … Bin Zheng and Yuchen Qiu review and revise the manuscript. …

Becoming invisible at will has fascinated humanity for centuries and in the past decade it
has attracted a great deal of attention owing to the advent of metamaterials. However, state-of-…