User profiles for Bradley W. Jacobs

W. Bradley Jacobs

University of Calgary
Verified email at ucalgary.ca
Cited by 2279

Does ending a posterior construct proximally at C2 versus C3 impact patient reported outcomes in degenerative cervical myelopathy patients up to 24 months after the …

…, N Evaniew, G McIntosh, BW Jacobs… - Global Spine …, 2023 - journals.sagepub.com
Study design Retrospective cohort study. Objectives The primary objective was to evaluate
the impact of the upper instrumented level (UIV) being at C2 vs C3 in posterior cervical …

Evaluation and treatment of spinal metastases: an overview

WB Jacobs, RG Perrin - Neurosurgical focus, 2001 - thejns.org
Metastases to the spine are a common and somber manifestation of systemic neoplasia. The
incidence of spinal metastases continues to increase, likely a result of increasing survival …

Ankylosing spondylitis and spinal cord injury: origin, incidence, management, and avoidance

WB Jacobs, MG Fehlings - Neurosurgical Focus, 2008 - thejns.org
✓ Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease that primarily
affects the vertebral column and sacroiliac joints. Over time, the disease process promotes …

Anterior versus posterior approach for treatment of cervical spondylotic myelopathy: a systematic review

BD Lawrence, WB Jacobs, DC Norvell, JT Hermsmeyer… - Spine, 2013 - journals.lww.com
Study Design. Systematic review. Objective. We performed a systematic review to determine
the comparative effectiveness and safety profiles of anterior versus posterior …

The impact of machine learning on patient care: a systematic review

D Ben-Israel, WB Jacobs, S Casha, S Lang… - Artificial intelligence in …, 2020 - Elsevier
Background Despite the expanding use of machine learning (ML) in fields such as finance
and marketing, its application in the daily practice of clinical medicine is almost non-existent. …

Systematic review of magnetic resonance imaging characteristics that affect treatment decision making and predict clinical outcome in patients with cervical …

…, A Singh, A Nouri, MG Fehlings, ED Brodt, WB Jacobs - Spine, 2013 - journals.lww.com
Objective. To determine whether there are magnetic resonance imaging (MRI) characteristics
in patients with cervical spondylotic myelopathy that affect treatment decisions or predict …

[HTML][HTML] p63 is an essential proapoptotic protein during neural development

WB Jacobs, G Govoni, D Ho, JK Atwal… - Neuron, 2005 - cell.com
The p53 family member p63 is required for nonneural development, but has no known role in
the nervous system. Here, we define an essential proapoptotic role for p63 during naturally …

The p53 family in nervous system development and disease

WB Jacobs, DR Kaplan, FD Miller - Journal of neurochemistry, 2006 - Wiley Online Library
The p53 family, consisting of the tumor suppressors p53, p63 and p73, play a vital role as
regulators of survival and apoptosis in the developing, adult and injured nervous system. …

ΔNp63 plays an anti-apoptotic role in ventral bladder development

W Cheng, WB Jacobs, JJR Zhang, A Moro, JH Park… - 2006 - journals.biologists.com
The bladder, the largest smooth-muscle organ in the human body, is responsible for urine
storage and micturition. P63, a homolog of the p53 tumor-suppressor gene, is essential for the …

[HTML][HTML] Preoperative factors predict postoperative trajectories of pain and disability following surgery for degenerative lumbar spinal stenosis

…, CG Fisher, YR Rampersaud, KC Thomas, WB Jacobs… - Spine, 2020 - journals.lww.com
Study Design. Longitudinal analysis of prospectively collected data. Objective. Investigate
potential predictors of poor outcome following surgery for degenerative lumbar spinal stenosis …