Pathology of colorectal cancer
MP De Leon, C Di Gregorio - Digestive and Liver Disease, 2001 - Elsevier
The earliest phases of colorectal tumourigenesis initiate in the normal mucosa, with a
generalised disorder of cell replication, and with the appearance of clusters of enlarged crypts (…
generalised disorder of cell replication, and with the appearance of clusters of enlarged crypts (…
Microsatellite instability and colorectal cancer prognosis
Purpose: Many studies have evaluated the role of high levels of microsatellite instability (MSI)
as a prognostic marker and predictor of the response to chemotherapy in colorectal cancer …
as a prognostic marker and predictor of the response to chemotherapy in colorectal cancer …
Mucin expression in peripheral airways of patients with chronic obstructive pulmonary disease
G Caramori, C Di Gregorio, I Carlstedt… - …, 2004 - Wiley Online Library
Aims: To study the expression of mucins in peripheral airways in patients with chronic
obstructive pulmonary disease (COPD). Methods and results: Peripheral lung sections from …
obstructive pulmonary disease (COPD). Methods and results: Peripheral lung sections from …
Gastric dysplasia. A follow-up study.
C Di Gregorio, P Morandi, R Fante… - American Journal of …, 1993 - search.ebscohost.com
… in addition, the nuclcus:c>toplasm ratio and the mitotic activitv increase, CcW straiillca- …
v\as found, and well-dilTerentiated atlenocarcmoma was diagnosctl after IM months, .-Mi …
v\as found, and well-dilTerentiated atlenocarcmoma was diagnosctl after IM months, .-Mi …
Cancer risk associated with STK11/LKB1 germline mutations in Peutz–Jeghers syndrome patients: Results of an Italian multicenter study
…, EL Cordisco, MG Tibiletti, C Di Gregorio… - Digestive and Liver …, 2013 - Elsevier
BACKGROUND: Germline mutations in the STK11/LKB1 gene cause Peutz–Jeghers
syndrome, an autosomal-dominantly inherited condition characterized by mucocutaneous …
syndrome, an autosomal-dominantly inherited condition characterized by mucocutaneous …
Microsatellite instability in gastric cancer is associated with better prognosis in only stage II cancers
…, A Tomezzoli, F Roviello, C Di Gregorio, C Vindigni… - Surgery, 2006 - Elsevier
BACKGROUND: The assessment of microsatellite instability (MSI) is not included yet in the
routine evaluation of patients with gastric cancer, as controversial data exist regarding its …
routine evaluation of patients with gastric cancer, as controversial data exist regarding its …
Clinical outcome of low-and high-risk malignant colorectal polyps: results of a population-based study and meta-analysis of the available literature
C Di Gregorio, LR Bonetti, C de Gaetani… - Internal and emergency …, 2014 - Springer
Some histological features of malignant polyps have been used to classify patients into low-
and high-risk groups. This study proposed to evaluate the impact of this classification on the …
and high-risk groups. This study proposed to evaluate the impact of this classification on the …
Identification of Muir–Torre syndrome among patients with sebaceous tumors and keratoacanthomas: role of clinical features, microsatellite instability, and …
… Carmela Di Gregorio MD … In 1 patient (Patient 2, Table 3), a constitutional mutation (2133
C→T) in exon 13 of the MSH2 gene could be detected. Two more patients (Patients 3 and 5) …
C→T) in exon 13 of the MSH2 gene could be detected. Two more patients (Patients 3 and 5) …
Myeloperoxidase-positive cell infiltration in colorectal carcinogenesis as indicator of colorectal cancer risk
…, A Bertani, A Merighi, P Benatti, C Di Gregorio… - … Biomarkers & Prevention, 2008 - AACR
Colorectal mucosa is targeted by toxic agents, which can initiate or promote colon cancer.
The mechanism of damage might be a focal irritation with loss of normal epithelial cell barrier …
The mechanism of damage might be a focal irritation with loss of normal epithelial cell barrier …
[HTML][HTML] Trend of incidence, subsite distribution and staging of colorectal neoplasms in the 15-year experience of a specialised cancer registry
…, G Rossi, M Menigatti, M Pedroni, C Di Gregorio… - Annals of …, 2004 - Elsevier
Background Two-thirds of colorectal malignancies are localised in the left colon and rectum.
Recent studies suggest a trend towards an increase of right-sided tumours which might …
Recent studies suggest a trend towards an increase of right-sided tumours which might …