[HTML][HTML] Immunotherapy for sarcomas: new frontiers and unveiled opportunities

…, S Cortés-Kaplan, J Werier, C Nessim… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Sarcomas are a rare malignancy of mesenchymal tissues, comprizing a plethora of unique
subtypes, with more than 60 types. The sheer heterogeneity of disease phenotype makes this …

[HTML][HTML] Retroperitoneal sarcoma care in 2021

E Schmitz, C Nessim - Cancers, 2022 - mdpi.com
Simple Summary Soft-tissue sarcomas are exceedingly rare, accounting for <1% of all adult
malignancies. Sarcomatous tumors are located within the retroperitoneum in <10% of cases. …

Management of primary retroperitoneal sarcoma (RPS) in the adult: an updated consensus approach from the Transatlantic Australasian RPS Working Group

…, E Stoeckle, JB Park, M Albertsmeier, C Nessim… - Annals of surgical …, 2021 - Springer
Background Retroperitoneal soft tissue sarcomas comprise a heterogeneous group of rare
tumors of mesenchymal origin that include several well-defined histologic subtypes. In 2015, …

Management of locally recurrent retroperitoneal sarcoma in the adult: an updated consensus approach from the Transatlantic Australasian Retroperitoneal Sarcoma …

…, WJ van Houdt, M Fau, C Nessim… - Annals of surgical …, 2022 - Springer
Background Surgery is the mainstay of treatment for retroperitoneal sarcoma (RPS), but local
recurrence is common. Biologic behavior and recurrence patterns differ significantly among …

Predicting survival in patients undergoing resection for locally recurrent retroperitoneal sarcoma: a study and novel nomogram from TARPSWG

…, E Stoeckle, A De Paoli, VG Pillarisetty, C Nessim… - Clinical cancer …, 2019 - AACR
Purpose: The role of surgery for first relapse locally recurrent retroperitoneal sarcoma (RPS-LR1)
is uncertain. We report outcomes of the largest RPS-LR1 series and propose a new …

Greenness profile and whiteness assessment of the stability-indicating HPLC method for the assay of levetiracetam

AM Michael, HM Lotfy, CK Nessim - Microchemical Journal, 2023 - Elsevier
Adoption of green analytical techniques has been one of the primary goals of the analytical
chemistry community over the past years. The reduction of waste generated during sample …

Clinical outcomes and risk stratification of early-stage melanoma micrometastases from an international multicenter study: implications for the management of …

…, AP Snelling, MJ Carr, C Nessim… - Journal of Clinical …, 2022 - ingentaconnect.com
… The C-statistic indicates that the discriminative performance of the model is such that the
higher the C-statistic, the better the model separates patients who will experience a clinical …

Dual inhibition of Wnt and Yes‐associated protein signaling retards the growth of triple‐negative breast cancer in both mesenchymal and epithelial states

…, J Dimitroulakos, A Arnaout, C Nessim… - Molecular …, 2018 - Wiley Online Library
… The conditions for RT-qPCR reactions were one cycle at 95 C for 20 s followed by 45 cycles
at 95 C for 3-s and annealing at 60 C for 30 s. Results were normalized to the housekeeping …

Radioactive seed localization versus wire-guided localization for nonpalpable breast cancer: a cost and operating room efficiency analysis

…, AM Ibrahim, A Arnaout, D Gravel, C Nessim - Annals of surgical …, 2017 - Springer
Background This study aimed to compare the cost and resource use between our first-year
experience using breast-conserving surgery (BCS) with radioactive seed localization (RSL) …

Primary excision margins, sentinel lymph node biopsy, and completion lymph node dissection in cutaneous melanoma: a clinical practice guideline

…, A Easson, C Murray, J Toye, D McCready, C Nessim… - Current …, 2019 - mdpi.com
Background: For patients who are diagnosed with early-stage cutaneous melanoma, the
principal therapy is wide surgical excision of the primary tumour and assessment of lymph …