Tests to detect the presence and activity of hepatitis B virus (HBV) are the cornerstones of
diagnosis and management. Assays that detect or measure serum levels of HB surface antigen…

Chronic infection with viral hepatitis affects half a billion individuals worldwide and can lead
to cirrhosis, cancer, and liver failure. Liver cancer is the third leading cause of cancer-…

The hepatitis B virus (HBV) is an important human pathogen. Unvaccinated infants infected
through mother‐to‐child transmission (MTCT) are at >95% risk of developing serum hepatitis …

OBJECTIVES: Few population-based studies have evaluated pyogenic liver abscess (PLA)
in North America. We assessed the incidence of PLA and evaluated predictors of mortality. …

Background & Aims GS-9620 is an oral agonist of toll-like receptor 7, a pattern-recognition
receptor whose activation results in innate and adaptive immune stimulation. We evaluated …

Background The 2016 World Health Assembly endorsed the elimination of hepatitis B virus (HBV)
infection as a public health threat by 2030; existing therapies and prophylaxis …

BACKGROUND: Although most patients with autoimmune hepatitis (AIH) respond to treatment
with prednisone and/or azathioprine, some patients are intolerant or refractory to standard …

Background Liver stiffness measurement (LSM) by transient elastography (TE, FibroScan) is
a validated method for noninvasively staging liver fibrosis. Most hepatic complications occur …

AIMS: Hydrogen sulphide (H 2 S) exerts several anti-inflammatory effects, accelerates the
healing of experimental gastric ulcers, and can stimulate intestinal secretion. Little is known …

Background & Aims Peginterferon lambda-1a (lambda) is a Type-III interferon, which, like
alfa interferons, has antiviral activity in vitro against hepatitis B virus (HBV) and hepatitis C …