In clinical terms, functional recovery after anterior cruciate ligament (ACL) injury is generally
poorer than after medial collateral ligament (MCL) injury. In experimental studies of injury, …

Functional outcomes of anterior cruciate ligament (ACL) injury are generally poorer than
those of medial collateral ligament (MCL) tears. Following ligament damage, all phases of …

Failed meniscal healing may lead to degenerative osteoarthritis of the knee. Healing is thought
to be dependent upon an adequate blood supply, yet “normal” vascular changes during …

Previous work has shown that innervation participates in normal ligament healing. The present
study was performed to determine if exogenous nerve growth factor (NGF) would improve …

Background Unplanned hospitalizations are common in patients with cardiovascular disease.
The “Triage Heart Failure Risk Status” (Triage‐HFRS) algorithm in patients with cardiac …

Background Articular cartilage has been the focus of multiple strategies to improve its
regenerative/ repair capacity. The Murphy Roths Large (MRL/MpJ) “super-healer” mouse …

Background Denervation substantially impairs healing of the medial collateral ligament (MCL).
Because normal ligaments are sparsely innervated, we hypothesized that neuropeptide-…

Previous experiments revealed that denervation impairs healing of the MCL. This suggested
the hypothesis that denervation would decrease repair‐associated mRNA levels in the …

Apposition of torn ligament ends has been shown to have a beneficial effect on healing of
the medial collateral ligament; however, the mechanism underlying this improved recovery is …

Loss of the posterior cruciate ligament (PCL) of the knee has a significant impact on joint
stability and biomechanical function. Changes in joint biomechanics may result in mal-adaptive …