We report a novel scanning ion conductance microscopy (SICM) technique for assessing
the volume of living cells, which allows quantitative, high-resolution characterization of …

Similar to healthy tissues, many blood and solid malignancies are now thought to be organised
hierarchically, with a subset of stem-like cancer cells that self-renew while giving rise to …

This multicenter phase II trial was designed to evaluate the activity of lapatinib in metastatic
breast cancer patients with HER2-negative primary tumors and HER2-positive circulating …

Members of the nuclear receptor superfamily are ligand-regulated transcription factors
involved in the control of a broad range of normal physiological and disease processes. The …

Integrins are upregulated on both tumor cells and associated vasculature, where they play
an important role in angiogenesis and metastasis. Fluciclatide is an arginine-glycine-aspartic …

Background Quantification of kinetic parameters of positron emission tomography (PET)
imaging agents normally requires collecting arterial blood samples which is inconvenient for …

Fulvestrant is a pure estrogen receptor (ER) antagonist with no agonist effects. We describe
the experience of a single center involving 45 postmenopausal women with advanced …

Accessible online at: www. karger. com/onk Fax+ 49 761 4 52 07 14 Information@ Karger. de
www. karger. com breast feed, younger age at first full-term pregnancy, use of medications …

A 24-year-old woman presented with a lump in the right breast. A right mastectomy and
axillary clearance with immediate reconstruction was performed. The operative specimen …

4-hydroxyandrostenedione, a potent inhibitor of the aromatase (oestrogen synthetase)
system, was given to 11 patients with metastatic breast cancer. After a single 500 mg …