Background Perioperative bleeding is common in patients undergoing noncardiac surgery.
Tranexamic acid is an antifibrinolytic drug that may safely decrease such bleeding. Methods …

Background Observational studies have suggested that accelerated surgery is associated
with improved outcomes in patients with a hip fracture. The HIP ATTACK trial assessed …

Importance Unrecognized obstructive sleep apnea increases cardiovascular risks in the
general population, but whether obstructive sleep apnea poses a similar risk in the …

Background Volatile (inhaled) anesthetic agents have cardioprotective effects, which might
improve clinical outcomes in patients undergoing coronary-artery bypass grafting (CABG). …

Background In non-surgical settings, covert stroke is more common than overt stroke and is
associated with cognitive decline. Although overt stroke occurs in less than 1% of adults after …

Background: Preliminary data suggest that preoperative N-terminal pro–B-type natriuretic
peptide (NT-proBNP) may improve risk prediction in patients undergoing noncardiac surgery. …

Background: Among patients having noncardiac surgery, perioperative hemodynamic
abnormalities are associated with vascular complications. Uncertainty remains about what …

Objective: To determine the prognostic relevance, clinical characteristics, and 30-day outcomes
associated with myocardial injury after noncardiac surgery (MINS) in vascular surgical …

Background Consensus recommendations regarding the threshold levels of cardiac troponin
elevations for the definition of perioperative myocardial infarction and clinically important …

Background Higher levels of inflammatory biomarkers are associated with an increased risk
of perioperative atrial fibrillation and myocardial injury after non-cardiac surgery (MINS). …