[HTML][HTML] Morbidity and mortality following pelvic ramus fractures in an older Atlantic Canadian cohort

CB Hamilton, JD Harnett, NC Stone… - Canadian Journal of …, 2019 - ncbi.nlm.nih.gov
Background Pelvic ramus fractures in older patients are associated with substantial morbidity
and mortality. There is a paucity of literature on fractures of the pelvis in this age group. The …

Methylglyoxal resistance in Bacillus subtilis: contributions of bacillithiol‐dependent and independent pathways

P Chandrangsu, R Dusi, CJ Hamilton… - Molecular …, 2014 - Wiley Online Library
Methylglyoxal ( MG ) is a toxic by‐product of glycolysis that damages DNA and proteins
ultimately leading to cell death. Protection from MG is often conferred by a glutathione‐…

Secular dynamics of binaries in stellar clusters–III. Doubly averaged dynamics in the presence of general-relativistic precession

C Hamilton, RR Rafikov - Monthly Notices of the Royal …, 2021 - academic.oup.com
… The DA approximation will be relaxed in an upcoming paper (Hamilton & Rafikov, in
preparation). This study complements our investigation of DA cluster tide-driven dynamics of …

Bacillithiol is an antioxidant thiol produced in Bacilli

…, VK Jothivasan, T Budiarto, CJ Hamilton… - Nature chemical …, 2009 - nature.com
… The reductase system responsible for maintaining BSH in the reduced state is not readily
identified in B. subtilis. As pointed out previously, B. subtilis lacks homologs of … Chris J Hamilton

Does chemotherapy improve survival in high-risk stage I and II Merkel cell carcinoma of the skin?

…, I Porter, E Walpole, J Harvey, C Hamilton… - International Journal of …, 2006 - Elsevier
Purpose: The effectiveness of synchronous carboplatin, etoposide, and radiation therapy in
improving survival was evaluated by comparison of a matched set of historic control subjects …

Nucleoside triphosphate mimicry: a sugar triazolyl nucleoside as an ATP-competitive inhibitor of B. anthracis pantothenate kinase

…, WA Wlassoff, A Claiborne, CJ Hamilton - Organic & …, 2009 - pubs.rsc.org
The synthesis of a library of nucleoside triphoshate mimetics is described where the Mg2+
chelated triphosphate sidechain is replaced by an uncharged methylene-triazole linked …

S-Bacillithiolation Protects Conserved and Essential Proteins Against Hypochlorite Stress in Firmicutes Bacteria

…, D Becher, D Albrecht, CJ Hamilton… - Antioxidants & redox …, 2013 - liebertpub.com
Aims: Protein S-bacillithiolations are mixed disulfides between protein thiols and the bacillithiol
(BSH) redox buffer that occur in response to NaOCl in Bacillus subtilis. We used BSH-…

[PDF][PDF] Chemical and chemoenzymatic syntheses of bacillithiol: A unique low‐molecular‐weight thiol amongst low G+ C gram‐positive bacteria

…, M Rawat, JJ La Clair, CJ Hamilton - Angewandte Chemie …, 2011 - academia.edu
In eukaryotes and Gram-negative bacteria, the cysteinyl tripeptide glutathione (GSH, Figure
1) is the predominant low-molecular-weight thiol. It plays a critical role in maintaining an …

Activity of 7-methyljuglone derivatives against Mycobacterium tuberculosis and as subversive substrates for mycothiol disulfide reductase

…, B Binneman, PB Fourie, CJ Hamilton… - Bioorganic & medicinal …, 2007 - Elsevier
The naphthoquinone 7-methyljuglone (5-hydroxy-7-methyl-1,4-naphthoquinone) has
previously been isolated and identified as an active component of root extracts of Euclea …

An evaluation of sampling effects on multiple DNA barcoding methods leads to an integrative approach for delimiting species: a case study of the North American …

CA Hamilton, BE Hendrixson, MS Brewer… - Molecular Phylogenetics …, 2014 - Elsevier
… The details of the phylogeny and the discussion of species relationships will be outlined in
a future taxonomic revision of the genus by Hamilton, Hendrixson, and Bond (in preparation). …