Effects of hypoxia-induced intrauterine growth restriction on cardiopulmonary structure and function during adulthood

CF Rueda-Clausen, JS Morton… - Cardiovascular …, 2009 - academic.oup.com
Aims Intrauterine growth restriction (IUGR), a condition affecting 7–15% of all pregnancies,
is associated with an increased mortality rate during adulthood. Several animal models have …

Hypoxia-Induced Intrauterine Growth Restriction Increases the Susceptibility of Rats to High-Fat Diet–Induced Metabolic Syndrome

CF Rueda-Clausen, VW Dolinsky, JS Morton… - Diabetes, 2011 - Am Diabetes Assoc
OBJECTIVE It is recognized that there is a remarkable variability in the systemic response to
high-fat (HF) diets that cannot be completely explained by genetic factors. In addition, …

[HTML][HTML] Weight loss required by the severely obese to achieve clinically important differences in health-related quality of life: two-year prospective cohort study

…, JA Johnson, CB Agborsangaya, CF Rueda-Clausen… - BMC medicine, 2014 - Springer
Background Guidelines and experts describe 5% to 10% reductions in body weight as `clinically
important’; however, it is not clear if 5% to 10% weight reductions correspond to …

Sildenafil Citrate Rescues Fetal Growth in the Catechol-O-Methyl Transferase Knockout Mouse Model

…, IJ Andersson, R Poudel, CF Rueda-Clausen… - …, 2012 - Am Heart Assoc
Preeclampsia and fetal growth restriction are responsible for the majority of maternal and
perinatal morbidity and mortality associated with complicated pregnancies. Although their …

Long-term effects of intrauterine growth restriction on cardiac metabolism and susceptibility to ischaemia/reperfusion

CF Rueda-Clausen, JS Morton… - Cardiovascular …, 2011 - academic.oup.com
Aims Adult offspring who are born intrauterine growth restricted (IUGR) are at risk of developing
cardiovascular diseases during adulthood. Additionally, several cardiac diseases are …

Health benefits of long-term weight-loss maintenance

CF Rueda-Clausen, AA Ogunleye… - Annual review of …, 2015 - annualreviews.org
Obesity is a chronic and complex medical condition associated with a large number of
complications affecting most organs and systems through multiple pathways. Strategies for weight …

[HTML][HTML] Effects of resveratrol in pregnancy using murine models with reduced blood supply to the uterus

R Poudel, JL Stanley, CF Rueda-Clausen… - PLOS …, 2013 - journals.plos.org
Preeclampsia (PE) and fetal growth restriction (FGR) contribute significantly to fetal and
maternal morbidity and mortality. Although the causes of PE and FGR are not fully understood, …

Mechanisms of endothelium-dependent vasodilation in male and female, young and aged offspring born growth restricted

JS Morton, CF Rueda-Clausen… - American Journal of …, 2010 - journals.physiology.org
Numerous epidemiological studies have shown that cardiovascular dysfunction in adult life
may be programmed by compromised growth in utero. Aging is a risk factor for vascular …

Continued postnatal administration of resveratrol prevents diet-induced metabolic syndrome in rat offspring born growth restricted

VW Dolinsky, CF Rueda-Clausen, JS Morton… - Diabetes, 2011 - Am Diabetes Assoc
OBJECTIVE A prenatal hypoxic insult leading to intrauterine growth restriction (IUGR) increases
the susceptibility to develop metabolic syndrome (MetS) later in life. Since resveratrol (…

The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors

CF Rueda-Clausen, V Lahera, J Calderón… - International journal of …, 2010 - Elsevier
… Author links open overlay panel Christian F. Rueda-Clausen a b 1 , Vicente Lahera b ,
Jaime Calderón c , Isabel Cristina Bolivar a , Victor R. Castillo c , Melquisedec Gutiérrez c , …