Importance The recent development of targeted therapy and immunotherapy has made
neoadjuvant therapy an attractive option for patients with hepatocellular carcinoma (HCC). …

Background The incidence of colorectal cancer in North America is rising among patients
younger than 50 years. Available data are conflicting regarding presentation and outcomes in …

Background Up to two thirds of patients presenting for abdominal cancer surgery are
malnourished pre‐operatively. Perioperative nutritional supplementation has been proposed to …

Background Recent practice guidelines recommend venous thromboembolism prophylaxis
for 28 days after cancer surgery. We sought to characterize and compare awareness, …

Background: The coronavirus disease 2019 (COVID-19) pandemic has had major implications
for general surgery practice. We sought to characterize general surgeons’ perceptions of …

Background Laparoscopic hepatectomy (LH) has been deemed safe, and, in the case of minor
hepatectomy, the standard of care. Short-, long-term outcomes and costs of LH compared …

Background: Some population-based recruitment methods, such as registries and databases,
have been used to increase enrolment in clinical trials by identifying eligible participants …

The lymphotoxin-alpha beta complex (LT alpha beta) is found on the surface of activated
lymphocytes and binds to a specific receptor called the LT beta receptor (LT beta R). In the …

Surface lymphotoxin (LT) is a heteromeric complex of LT-alpha and LT-beta chains that binds
to the LT-beta receptor (LT-beta-R), a member of the tumor necrosis factor (TNF) family of …

Cultures of bovine pulmonary endothelial (BPE) cells were exposed to LC 70 doses of ricin
or abrin (15.5 and 4.5 pM respectively) over a period of up to 40 h. The viability of the …