Mediators involved in the generation of symptoms in patients with irritable bowel syndrome (IBS)
are poorly understood. Here we show that colonic biopsy samples from IBS patients …

We have updated both the American College of Gastroenterology (ACG) and the Canadian
Association of Gastroenterology (CAG) guidelines on dyspepsia in a joint ACG/CAG …

Constipation is broadly defined as an unsatisfactory defecation characterized by infrequent
stools, difficult stool passage or both. The common approach to the pathophysiology of …

Background Cannabinoids are used by patients with inflammatory bowel disease (IBD) to
alleviate their symptoms. Little is known on patient motivation, benefit, or risks of this practice. …

Background & aims Irritable bowel syndrome (IBS) is one of the most common gastrointestinal
(GI) disorders, affecting about 10% of the general population globally. The aim of this …

BACKGROUND: The incidence of primary extranodal non-Hodgkin lymphoma (NHL) of the
gastrointestinal (GI) tract has been on the rise.OBJECTIVES: To determine the incidence of …

OBJECTIVES: Prokinetics are considered the preferred treatment option for gastroparesis,
but evidence of their efficacy is scarce. Prucalopride, a selective 5-hydroxytryptamine 4 …

Chronic nausea and vomiting syndromes (NVSs) are prevalent and debilitating disorders.
Putative mechanisms include gastric neuromuscular disease and dysregulation of brain-gut …

Background & Aims: Irritable bowel syndrome (IBS) has been associated with mucosal
dysfunction, mild inflammation, and altered colonic bacteria. We used microarray expression …

Background and Purpose Chronic gastric symptoms are common, however differentiating
specific contributing mechanisms in individual patients remains challenging. Abnormal gastric …