Various magnetic resonance (MR) techniques are used to study the pathological evolution
of demyelinating diseases, such as multiple sclerosis (MS). However, few studies have …

Background: Measurements of the T 2 decay curve provide estimates of total water content
and myelin water fraction in white matter in-vivo, which may help in understanding the …

Myelin water imaging (MWI) promises to be invaluable in understanding neurological
diseases like MS. However, a limitation of MWI is signal to noise ratio. Recently, a number of …

The ability to measure myelin in vivo has great consequences for furthering our knowledge
of normal development, as well as for understanding a wide range of neurological disorders. …

T 2 weighting is particularly sensitive, but notoriously unspecific, to a wide range of brain
pathologies. However, careful measurement and analysis of the T 2 decay curve from brain …

Myelin is critical for healthy brain function. An accurate in vivo measure of myelin content has
important implications for understanding brain plasticity and neurodegenerative diseases. …

Purpose To investigate the correlation between water content (WC) and magnetization transfer
ratio (MTR) in normal and multiple sclerosis (MS) brain. The MTR has been proposed as …

Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges,
including a lack of standardized imaging protocols. Here we present a prospectively …

Spinal cord involvement is an important cause of disability in patients with multiple sclerosis
or neuromyelitis optica spectrum disorders (NMOSDs). Multiple sclerosis and NMOSDs can …

Purpose Myelin water fraction is conventionally measured from the T 2 decay curve.
Recently, a steady‐state approach entitled multicomponent‐driven equilibrium single pulse …