Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Crohn’s disease and ulcerative colitis, the two common forms of inflammatory bowel disease
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
…, HJ Westra, RJ Xavier, ZZ Zhao, CY Ponsioen… - Nature …, 2011 - nature.com
Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…
Findings from a randomized controlled trial of fecal transplantation for patients with ulcerative colitis
…, EG Zoetendal, GR D'Haens, CY Ponsioen - Gastroenterology, 2015 - Elsevier
Background & Aims Several case series have reported the effects of fecal microbiota
transplantation (FMT) for ulcerative colitis (UC). We assessed the efficacy and safety of FMT for …
transplantation (FMT) for ulcerative colitis (UC). We assessed the efficacy and safety of FMT for …
[HTML][HTML] The EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality
…, MA Dirac, A Belloni, M Serra-Burriel, CY Ponsioen… - The Lancet, 2022 - thelancet.com
Liver diseases have become a major health threat across Europe, and the face of European
hepatology is changing due to the cure of viral hepatitis C and the control of chronic viral …
hepatology is changing due to the cure of viral hepatitis C and the control of chronic viral …
[HTML][HTML] Epidemiology of primary sclerosing cholangitis and primary biliary cirrhosis: a systematic review
K Boonstra, U Beuers, CY Ponsioen - Journal of hepatology, 2012 - Elsevier
OBJECTIVE: Studies on the epidemiology of primary sclerosing cholangitis (PSC) and primary
biliary cirrhosis (PBC) show variable outcome. We aimed at systematically reviewing the …
biliary cirrhosis (PBC) show variable outcome. We aimed at systematically reviewing the …
Population-based epidemiology, malignancy risk, and outcome of primary sclerosing cholangitis
…, N van Geloven, U Beuers, CY Ponsioen… - Hepatology, 2013 - journals.lww.com
Extensive population-based studies are much needed to accurately establish epidemiology
and disease course in patients with primary sclerosing cholangitis (PSC). We aimed to …
and disease course in patients with primary sclerosing cholangitis (PSC). We aimed to …
Healthcare costs of inflammatory bowel disease have shifted from hospitalisation and surgery towards anti-TNFα therapy: results from the COIN study
…, AE van der Meulen-de, CY Ponsioen… - Gut, 2014 - gut.bmj.com
Objective The introduction of anti tumour necrosis factor-α (anti-TNFα) therapy might impact
healthcare expenditures, but there are limited data regarding the costs of inflammatory …
healthcare expenditures, but there are limited data regarding the costs of inflammatory …
Levels of alkaline phosphatase and bilirubin are surrogate end points of outcomes of patients with primary biliary cirrhosis: an international follow-up study
Background & Aims Noninvasive surrogate end points of long-term outcomes of patients
with primary biliary cirrhosis (PBC) are needed to monitor disease progression and evaluate …
with primary biliary cirrhosis (PBC) are needed to monitor disease progression and evaluate …
Patient age, sex, and inflammatory bowel disease phenotype associate with course of primary sclerosing cholangitis
Background & Aims Primary sclerosing cholangitis (PSC) is an orphan hepatobiliary
disorder associated with inflammatory bowel disease (IBD). We aimed to estimate the risk of …
disorder associated with inflammatory bowel disease (IBD). We aimed to estimate the risk of …
Development and validation of a scoring system to predict outcomes of patients with primary biliary cirrhosis receiving ursodeoxycholic acid therapy
…, KD Lindor, HLA Janssen, A Floreani, CY Ponsioen… - Gastroenterology, 2015 - Elsevier
Background & Aims Approaches to risk stratification for patients with primary biliary cirrhosis
(PBC) are limited, single-center based, and often dichotomous. We aimed to develop and …
(PBC) are limited, single-center based, and often dichotomous. We aimed to develop and …
