Isomaltulose is a natural occurring disaccharide composed of α-1,6-linked glucose and
fructose. Commercial isomaltulose is produced from sucrose by enzymatic rearrangement and …

Background and purpose Most research regarding child and adolescent mental health
prevention and promotion in low-and middle-income countries is undertaken in high-income …

Background Treatment with cetuximab, a monoclonal antibody directed against the epidermal
growth factor receptor, improves overall and progression-free survival and preserves the …

The objective of this systematic review was to provide current evidence regarding the use of
adjuvant systemic chemotherapy for stage II and III colon cancer following curative intent …

Background Cetuximab, an IgG1 chimeric monoclonal antibody against epidermal growth
factor receptor (EGFR), has activity against colorectal cancers that express EGFR. Methods …

Background Elderly patients are often under-represented in clinical trials of metastatic colorectal
cancer. We aimed to assess the efficacy and safety of bevacizumab plus capecitabine …

… Because the glycine (G)-to-aspartate (D) transition mutation is the most frequent codon
13 mutation in colorectal cancer, 5 we studied the association of this p.G13D mutation with …

The efficacy and safety of biological molecules in cancer therapy, such as peptides and small
interfering RNAs (siRNAs), could be markedly increased if high concentrations could be …

Purpose: To compare the performance of the standard lag time model (LAG model) with the
performance of an analytical solution of the transit compartment model (TRANSIT model) in …

… (a–d) Kaplan–Meier curves showing the relationship between the primary site of tumour (right-
(RC) versus left-… (D) Comparing PFS in all LC patients receiving cetuximab versus BSC. …