To comprehend the results of a randomised controlled trial (RCT), readers must understand
its design, conduct, analysis, and interpretation. That goal can be achieved only through …

Background The Quality of Reporting of Meta-analyses (QUOROM) conference was convened
to address standards for improving the quality of reporting of meta-analyses of clinical …

ObjectiveBecause of the pressure for timely, informed decisions in public health and clinical
practice and the explosion of information in the scientific literature, research results must be …

Background Systematic reviews (SRs) have become increasingly popular to a wide range
of stakeholders. We set out to capture a representative cross-sectional sample of published …

Overwhelming evidence shows the quality of reporting of randomised controlled trials (RCTs)
is not optimal. Without transparent reporting, readers cannot judge the reliability and …

Moher and colleagues introduce PRISMA (Preferred Reporting Items for Systematic
Reviews and Meta-Analyses), an update of the QUOROM guidelines for reporting systematic …

Randomised controlled trials, when appropriately designed, conducted and reported,
represent the gold standard in evaluating healthcare interventions. However, randomised trials …

Flaws in the design, conduct, analysis, and reporting of randomised trials can cause the
effect of an intervention to be underestimated or overestimated. The Cochrane Collaboration’s …

The PRISMA statement is a reporting guideline designed to improve the completeness of
reporting of systematic reviews and meta-analyses. Authors have used this guideline …

Background Few meta-analyses of randomised trials assess the quality of the studies
included. Yet there is increasing evidence that trial quality can affect estimates of intervention …