The evolution of cell death programs as prerequisites of multicellularity

S Huettenbrenner, S Maier, C Leisser, D Polgar… - … Research/Reviews in …, 2003 - Elsevier
One of the hallmarks of multicellularity is that the individual cellular fate is sacrificed for the
benefit of a higher order of life—the organism. The accidental death of cells in a multicellular …

Effects of zinc on the kinetics of branchial calcium uptake in freshwater rainbow trout during adaptation to waterborne zinc

C Hogstrand, RW Wilson, D Polgar… - Journal of …, 1994 - journals.biologists.com
… Subvention Program Grant to CMW, grants from Längmanska kulturfonden and Kungliga
Hvitfeldtska Stipendieinrättningen to CH, and a PDF from SJFR to CH We are grateful to Dr D. …

[HTML][HTML] Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside

M Grusch, D Polgar, S Gfatter, K Leuhuber… - Cell Death & …, 2002 - nature.com
A new synthetic drug, benzamide riboside (BR) exhibited strong oncolytic activity against
leukemic cells in the 5–10 μM range. Higher BR-concentrations (20 μM) predominantly …

Shaken baby syndrome and a triple-dose strategy for its prevention

TC Stewart, D Polgar, J Gilliland… - Journal of Trauma …, 2011 - journals.lww.com
Objectives: Inflicted traumatic brain injury associated with Shaken Baby Syndrome (SBS) is
a leading cause of injury mortality and morbidity in infants. A triple-dose SBS prevention …

FAS (CD95) mutations are rare in gastric MALT lymphoma but occur more frequently in primary gastric diffuse large B-cell lymphoma

…, D Sebinger, P Gruber, J Buch, D Polgar… - The American journal of …, 2004 - Elsevier
A loss of FAS (CD95) function has been proposed to constitute an important step in early
mucosa-associated lymphoid tissue (MALT) lymphoma development and FAS mutations have …

Transferrin ensures survival of ovarian carcinoma cells when apoptosis is induced by TNFα, FasL, TRAIL, or Myc

…, M Grusch, G Fuhrmann, K Leuhuber, D Polgar… - Oncogene, 2003 - nature.com
The activation of Myc induces apoptosis of human ovarian adenocarcinoma N. 1 cells when
serum factors are limited. However, the downstream mechanism that is triggered by Myc is …

[HTML][HTML] Subcellular localisation of Cdc25A determines cell fate

…, S Huettenbrenner, S Fassl, D Polgar… - Cell Death & …, 2004 - nature.com
Cell division cycle 25A (Cdc25A) was shown to colocalise both with nuclear and cytoplasmic
proteins. Recently, we have demonstrated that overexpressed Cdc25A promoted the …

Truncated ALK derived from chromosomal translocation t (2; 5)(p23; q35) binds to the SH3 domain of p85-PI3K

D Polgar, C Leisser, S Maier, S Strasser… - Mutation Research …, 2005 - Elsevier
The chromosomal translocation t(2;5)(p23;q35) is associated with “Anaplastic large cell
lymphomas” (ALCL), a Non Hodgkin Lymphoma occurring in childhood. The fusion of the …

Cell death mechanisms and potentially cytotoxic natural immune cells in human pregnancies complicated by preeclampsia

…, E Miko, L Szereday, PD Polgar… - Reproductive …, 2014 - journals.sagepub.com
Preeclampsia, which occurs in about 2% to 3% of all pregnancies, is a severe multisystem
disorder showing symptoms in the second half of human pregnancy. Its prevention, early …

Evaluation of an adolescent hospital-based injury prevention program

…, D Polgar, MJ Girotti, E Vingilis, D Caro… - Journal of Trauma …, 2009 - journals.lww.com
Background: IMPACT (Impaired Minds Produce Actions Causing Trauma) is an adolescent,
hospital-based program aimed to prevent injuries and their consequences caused by …