[HTML][HTML] Hepatitis C virus replication in mice with chimeric human livers
DF Mercer, DE Schiller, JF Elliott, DN Douglas, C Hao… - Nature medicine, 2001 - nature.com
Lack of a small animal model of the human hepatitis C virus (HCV) has impeded development
of antiviral therapies against this epidemic infection. By transplanting normal human …
of antiviral therapies against this epidemic infection. By transplanting normal human …
Differentiation and transplantation of human embryonic stem cell–derived hepatocytes
BACKGROUND & AIMS: The ability to obtain unlimited numbers of human hepatocytes would
improve the development of cell-based therapies for liver diseases, facilitate the study of …
improve the development of cell-based therapies for liver diseases, facilitate the study of …
West Nile Virus—Associated Encephalitis in Recipients of Renal and Pancreas Transplants: Case Series and Literature Review
…, AG Freifeld, AC Kalil, DF Mercer… - Clinical infectious …, 2004 - academic.oup.com
Although West Nile fever is mild in the vast majority of infected persons, there is growing
evidence that the disease may be more severe in the immunocompromised population. We …
evidence that the disease may be more severe in the immunocompromised population. We …
Current management of the short bowel syndrome
…, R Weseman, FA Rochling, DF Mercer - Surgical …, 2011 - surgical.theclinics.com
Intestinal failure from loss of intestine, or short bowel syndrome (SBS), is associated with the
inability to maintain protein, energy, fluid, electrolytes, or micronutrient balances while on a …
inability to maintain protein, energy, fluid, electrolytes, or micronutrient balances while on a …
[HTML][HTML] Outcomes from a 12-week, open-label, multicenter clinical trial of teduglutide in pediatric short bowel syndrome
…, C Duggan, S Hill, S Horslen, JD Lim, DF Mercer… - The Journal of …, 2017 - Elsevier
Objective To determine safety and pharmacodynamics/efficacy of teduglutide in children
with intestinal failure associated with short bowel syndrome (SBS-IF). Study design This 12-…
with intestinal failure associated with short bowel syndrome (SBS-IF). Study design This 12-…
[HTML][HTML] Characterization of the ileal microbiota in rejecting and nonrejecting recipients of small bowel transplants
…, Y Sun, J Walter, DA Peterson, DF Mercer - American Journal of …, 2012 - Elsevier
Small bowel transplantation can be a life-preserving procedure for patients with irreversible
intestinal failure. Allograft rejection remains a major source of morbidity and mortality and its …
intestinal failure. Allograft rejection remains a major source of morbidity and mortality and its …
[PDF][PDF] Left lobe adult‐to‐adult living donor liver transplantation: small grafts and hemiportocaval shunts in the prevention of small‐for‐size syndrome
…, CE Freise, NL Ascher, DF Mercer… - Liver …, 2010 - Wiley Online Library
Adult‐to‐adult living donor liver transplantation (AA‐LDLT) has better outcomes when a graft
weight to recipient weight ratio (GW/RW) > 0.8 is selected. A smaller GW/RW may result in …
weight to recipient weight ratio (GW/RW) > 0.8 is selected. A smaller GW/RW may result in …
Safety and efficacy of teduglutide in pediatric patients with intestinal failure due to short bowel syndrome: a 24‐week, phase III study
…, S Hu, SS Kaufman, DF Mercer… - Journal of Parenteral …, 2020 - Wiley Online Library
Background This study evaluated the safety and efficacy of teduglutide in pediatric patients
with short bowel syndrome–associated intestinal failure (SBS‐IF). Methods A 24‐week, …
with short bowel syndrome–associated intestinal failure (SBS‐IF). Methods A 24‐week, …
[PDF][PDF] HCV796: A selective nonstructural protein 5B polymerase inhibitor with potent anti‐hepatitis C virus activity In Vitro, in mice with chimeric human livers, and in …
…, D Pevear, G Lund, D Douglas, DF Mercer… - …, 2009 - Wiley Online Library
Anti‐hepatitis C virus (HCV) drug development has been challenged by a lack of experience
with inhibitors inclusive of in vitro, animal model, and clinical study. This manuscript …
with inhibitors inclusive of in vitro, animal model, and clinical study. This manuscript …
Is there a role for oral human immunoglobulin in the treatment for norovirus enteritis in immunocompromised patients?
…, D Gumeel, WJ Grant, DF Mercer… - Pediatric …, 2011 - Wiley Online Library
… Florescu DF, Hermsen ED, Kwon JY, Gumeel D, Grant WJ, Mercer DF, Kalil AC. Is there a
role for oral … Mercer: Participated in the writing of the paper and data analysis; Andre C. Kalil: …
role for oral … Mercer: Participated in the writing of the paper and data analysis; Andre C. Kalil: …