User profiles for David A. Seminowicz

David A. Seminowicz

University of Western Ontario, London, Ontario, Canada
Verified email at uwo.ca
Cited by 14341

Limbic–frontal circuitry in major depression: a path modeling metanalysis

DA Seminowicz, HS Mayberg, AR McIntosh… - Neuroimage, 2004 - Elsevier
This paper reports the results of an across lab metanalysis of effective connectivity in major
depression (MDD). Using FDG PET data and Structural Equation Modeling, a formal …

Two systems of resting state connectivity between the insula and cingulate cortex

KS Taylor, DA Seminowicz, KD Davis - Human brain mapping, 2009 - Wiley Online Library
The insula and cingulate cortices are implicated in emotional, homeostatic/allostatic,
sensorimotor, and cognitive functions. Non‐human primates have specific anatomical connections …

Accelerated brain gray matter loss in fibromyalgia patients: premature aging of the brain?

…, P Schweinhardt, DA Seminowicz… - Journal of …, 2007 - Soc Neuroscience
Fibromyalgia is an intractable widespread pain disorder that is most frequently diagnosed in
women. It has traditionally been classified as either a musculoskeletal disease or a …

Effective treatment of chronic low back pain in humans reverses abnormal brain anatomy and function

DA Seminowicz, TH Wideman, L Naso… - Journal of …, 2011 - Soc Neuroscience
Chronic pain is associated with reduced brain gray matter and impaired cognitive ability. In
this longitudinal study, we assessed whether neuroanatomical and functional abnormalities …

A neurocognitive model of attention to pain: behavioral and neuroimaging evidence

…, C Eccleston, KD Davis, DA Seminowicz… - Pain, 2009 - journals.lww.com
The perception of pain is the result of a complex dynamic system that codes, transports and
processes nociceptive signals. The relationship between nociceptive information and pain is …

Cortical responses to pain in healthy individuals depends on pain catastrophizing

DA Seminowicz, KD Davis - Pain, 2006 - Elsevier
The personal experience of pain is complex and depends on physiological and psychological
factors. From this latter category, pain catastrophizing plays an important role in pain …

[HTML][HTML] The dorsolateral prefrontal cortex in acute and chronic pain

DA Seminowicz, M Moayedi - The Journal of Pain, 2017 - Elsevier
The dorsolateral prefrontal cortex (DLPFC) is a functionally and structurally heterogeneous
region and a key node of several brain networks, implicated in cognitive, affective, and …

Regional gray matter density changes in brains of patients with irritable bowel syndrome

DA Seminowicz, JS Labus, JA Bueller, K Tillisch… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Several studies have examined structural brain changes associated
with chronic pain syndromes, including irritable bowel syndrome (IBS), but study sample …

[HTML][HTML] Cognitive-behavioral therapy increases prefrontal cortex gray matter in patients with chronic pain

DA Seminowicz, M Shpaner, ML Keaser… - The Journal of …, 2013 - Elsevier
Several studies have reported reduced cerebral gray matter (GM) volume or density in
chronic pain conditions, but there is limited research on the plasticity of the human cortex in …

MRI structural brain changes associated with sensory and emotional function in a rat model of long-term neuropathic pain

DA Seminowicz, AL Laferriere, M Millecamps, SC Jon… - Neuroimage, 2009 - Elsevier
In human conditions, chronic pain is associated with widespread anatomical changes in the
brain. Nevertheless, little is known about the time course of these changes or the …