User profiles for David Brandman

David Brandman

Division of Neurosurgery
Verified email at dal.ca
Cited by 669

Home use of a percutaneous wireless intracortical brain-computer interface by individuals with tetraplegia

…, B Franco, JN Kelemen, DM Brandman… - IEEE Transactions …, 2021 - ieeexplore.ieee.org
Objective. Individuals with neurological disease or injury such as amyotrophic lateral sclerosis,
spinal cord injury or stroke may become tetraplegic, unable to speak or even locked-in. …

[HTML][HTML] Specific lipids supply critical negative spontaneous curvature—An essential component of native Ca2+-triggered membrane fusion

MA Churchward, T Rogasevskaia, DM Brandman… - Biophysical journal, 2008 - cell.com
The Ca 2+ -triggered merger of two apposed membranes is the defining step of regulated
exocytosis. CHOL is required at critical levels in secretory vesicle membranes to enable …

Rapid calibration of an intracortical brain–computer interface for people with tetraplegia

DM Brandman, T Hosman, J Saab… - Journal of neural …, 2018 - iopscience.iop.org
Objective. Brain–computer interfaces (BCIs) can enable individuals with tetraplegia to
communicate and control external devices. Though much progress has been made in improving …

human intracortical recording and neural decoding for brain–computer interfaces

DM Brandman, SS Cash… - IEEE Transactions on …, 2017 - ieeexplore.ieee.org
Brain-computer interfaces (BCIs) use neural information recorded from the brain for the
voluntary control of external devices. The development of BCI systems has largely focused on …

BCI decoder performance comparison of an LSTM recurrent neural network and a Kalman filter in retrospective simulation

…, D Milstein, JN Kelemen, DM Brandman… - … EMBS conference on …, 2019 - ieeexplore.ieee.org
Intracortical brain computer interfaces (iBCIs) using linear Kalman decoders have enabled
individuals with paralysis to control a computer cursor for continuous point-and-click typing on …

[HTML][HTML] Decoding speech from spike-based neural population recordings in secondary auditory cortex of non-human primates

…, J Lee, R O'Shea, L Lynch, DM Brandman… - Communications …, 2019 - nature.com
Direct electronic communication with sensory areas of the neocortex is a challenging
ambition for brain-computer interfaces. Here, we report the first successful neural decoding of …

Copper (II) sulfate charring for high sensitivity on-plate fluorescent detection of lipids and sterols: quantitative analyses of the composition of functional secretory …

MA Churchward, DM Brandman… - Journal of chemical …, 2008 - Springer
A wide range of methods exist for the on-plate detection of lipids resolved by thin layer
chromatography. Fluorescence generally offers improvements in sensitivity over methods that use …

[HTML][HTML] Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells

…, LP Westhaver, EL Castle, DM Brandman… - Cell death & …, 2020 - nature.com
Glioblastoma (GBM) is the most common primary malignant brain tumor, and it has a uniformly
poor prognosis. Hypoxia is a feature of the GBM microenvironment, and previous work …

Synthesizing speech by decoding intracortical neural activity from dorsal motor cortex

…, LR Hochberg, DM Brandman… - 2023 11th …, 2023 - ieeexplore.ieee.org
Losing the ability to speak due to brain injury or neurodegenerative diseases such as ALS
can be debilitating. Brain-computer interfaces could potentially provide affected individuals a …

Spike train SIMilarity Space (SSIMS): a framework for single neuron and ensemble data analysis

CE Vargas-Irwin, DM Brandman, JB Zimmermann… - Neural …, 2015 - direct.mit.edu
Increased emphasis on circuit level activity in the brain makes it necessary to have methods
to visualize and evaluate large-scale ensemble activity beyond that revealed by raster-…