Background The goals of axillary-lymph-node dissection (ALND) are to maximise survival,
provide regional control, and stage the patient. However, this technique has substantial side-…

Background Most women with breast cancer who undergo breast-conserving surgery receive
whole-breast irradiation. We examined whether the addition of regional nodal irradiation to …

Aberrant activation of Notch receptors has been shown to cause mammary tumors in mice.
We therefore used in situ hybridization to analyze expression of Notch ligands and receptors …

Purpose An increasing proportion of patients (> 30%) with node-positive breast cancer will
obtain an axillary pathologic complete response after neoadjuvant chemotherapy (NAC). If …

Background We determined the effect of breast irradiation plus tamoxifen on disease-free
survival and local relapse in women 50 years of age or older who had T1 or T2 node-negative …

Purpose Cancer-related fatigue (CRF) is the most prevalent and distressing symptom among
cancer patients and survivors. However, research on its prevalence and related disability in …

Numerous studies have examined the relationship between organochlorines and breast
cancer, but the results are not consistent. In most studies,organochlorines were measured in …

Metformin may exert anti-cancer effects through indirect (insulin-mediated) or direct (insulin-independent)
mechanisms. We report results of a neoadjuvant “window of opportunity” study …

In 2001, an international conference panel comprised of an interdisciplinary group of
physicians specializing in the diagnosis and treatment of breast disease met to discuss their …

Purpose There is little consensus regarding preoperative magnetic resonance imaging (MRI)
in breast cancer (BC). We examined the association between preoperative MRI and local …