Alzheimer’s disease (AD) is the most common type of dementia and is characterized by the
aggregation of extracellular amyloid-beta and intracellular hyperphosphorylation of tau …

Background Frailty is associated with adverse outcomes including disability, mortality and risk
of falls. Trauma registries capture a broad range of injuries. However, frail patients who fall …

Background Frailty has been associated with an increased risk of adverse postoperative
outcomes in elderly patients. We examined the impact of preoperative frailty on loss of …

Objectives Readmission after acute care is a significant contributor to health care costs, and
has been proposed as a quality indicator. Our earlier studies showed that patients aged ≥…

Topic This systematic review and meta-analysis aims to clarify the association of cataract
surgery with cognitive impairment and dementia in adults with cataracts. Clinical Relevance …

Methods This research aims to actively engage stakeholders (including doctors, physiotherapists,
hip fracture patients, and caregivers) using the systems modeling methodology of …

Background Survivors of trauma are at increased risk of dying after discharge. Studies have
found that age, head injury, injury severity, falls and co-morbidities predict long-term mortality…

Objective Frailty is associated with morbidity and mortality in older injured patients. However,
for older blunt-trauma patients, increased frailty may not manifest in longer length of stay at …

Background Patients suffering moderate or severe injury after low falls have higher readmission
and long-term mortality rates compared to patients injured by high-velocity mechanisms …

Objectives Family caregivers play a fundamental role in the care of the older blunt trauma
patient. We aim to identify risk factors for negative and positive experiences of caregiving …