Endothelial activation and blood–brain barrier disruption in neurotoxicity after adoptive immunotherapy with CD19 CAR-T cells
Lymphodepletion chemotherapy followed by infusion of CD19-targeted chimeric antigen
receptor–modified T (CAR-T) cells can be complicated by neurologic adverse events (AE) in …
receptor–modified T (CAR-T) cells can be complicated by neurologic adverse events (AE) in …
[HTML][HTML] Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura
X Zheng, D Chung, TK Takayama, EM Majerus… - Journal of Biological …, 2001 - ASBMB
Thrombotic thrombocytopenic purpura is associated with acquired or congenital deficiency
of a plasma von Willebrand factor-cleaving protease (VWFCP). Based on partial amino acid …
of a plasma von Willebrand factor-cleaving protease (VWFCP). Based on partial amino acid …
Kinetics and biomarkers of severe cytokine release syndrome after CD19 chimeric antigen receptor–modified T-cell therapy
Lymphodepletion chemotherapy followed by infusion of CD19-specific chimeric antigen
receptor–modified (CAR) T cells has produced impressive antitumor responses in patients with …
receptor–modified (CAR) T cells has produced impressive antitumor responses in patients with …
Purification of human von Willebrand factor–cleaving protease and its identification as a new member of the metalloproteinase family
…, H Suzuki, B McMullen, D Chung - Blood, The Journal of …, 2001 - ashpublications.org
von Willebrand factor (vWF) is synthesized in megakaryocytes and endothelial cells as a
very large multimer, but circulates in plasma as a group of multimers ranging from 500 to 10 …
very large multimer, but circulates in plasma as a group of multimers ranging from 500 to 10 …
Role of fibrinogen alpha and gamma chain sites in platelet aggregation.
…, P Thiagarajan, DW Chung… - Proceedings of the …, 1992 - National Acad Sciences
Fibrinogen (Fbg) mediates platelet aggregation by its interaction with the platelet glycoprotein
IIb-IIIa (integrin alpha IIb beta 3). Peptides containing the amino acid sequence RGD …
IIb-IIIa (integrin alpha IIb beta 3). Peptides containing the amino acid sequence RGD …
[HTML][HTML] Factor XI deficiency in Ashkenazi jews in Israel
R Asakai, DW Chung, EW Davie… - New England Journal …, 1991 - Mass Medical Soc
Background and Methods. Severe factor XI deficiency, which is relatively common among
Ashkenazi Jews, is associated with injury-related bleeding of considerable severity. Three …
Ashkenazi Jews, is associated with injury-related bleeding of considerable severity. Three …
Amino acid sequence of human factor XI, a blood coagulation factor with four tandem repeats that are highly homologous with plasma prekallikrein
K Fujikawa, DW Chung, LE Hendrickson… - Biochemistry, 1986 - ACS Publications
Department of Biochemistry, University of Washington, Seattle, Washington 98195 Received
November 21, 1985; Revised Manuscript Received January 10, 1986 abstract: A Xgtl 1 …
November 21, 1985; Revised Manuscript Received January 10, 1986 abstract: A Xgtl 1 …
Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity
…, K Fujikawa, W Xu, DW Chung… - Proceedings of the …, 1999 - National Acad Sciences
The activation of human platelets by thrombin is mediated primarily by protease-activated
receptors (PARs). PAR1 and PAR4 are present on human platelets and are activated by the …
receptors (PARs). PAR1 and PAR4 are present on human platelets and are activated by the …
Cloning of the alpha chain of human platelet glycoprotein Ib: a transmembrane protein with homology to leucine-rich alpha 2-glycoprotein.
JA Lopez, DW Chung, K Fujikawa… - Proceedings of the …, 1987 - National Acad Sciences
Glycoprotein Ib is a surface membrane glycoprotein of platelets that functions as a receptor
for von Willebrand factor. It is a heterodimer composed of an alpha and a beta chain linked …
for von Willebrand factor. It is a heterodimer composed of an alpha and a beta chain linked …
[HTML][HTML] Crystal structure of a 30 kDa C-terminal fragment from the γ chain of human fibrinogen
Background: Blood coagulation occurs by a cascade of zymogen activation resulting from
minor proteolysis. The final stage of coagulation involves thrombin generation and limited …
minor proteolysis. The final stage of coagulation involves thrombin generation and limited …
