User profiles for E. Wakeam

Elliot Wakeam

University of Toronto
Verified email at uhn.ca
Cited by 1545

Gene expression profiles in peripheral blood mononuclear cells can distinguish patients with non–small cell lung cancer from patients with nonmalignant lung disease

…, C Chang, J Kucharczuk, B Tran, E Wakeam… - Cancer research, 2009 - AACR
… , we found that 13 of 13 (P = 9.2E-06) differentially expressed antipathogen response genes
and 8 of 9 genes (P = 5.04E-04) associated with the generation of reactive oxidative species…

Failure to rescue in safety-net hospitals: availability of hospital resources and differences in performance

E Wakeam, ND Hevelone, R Maine, J Swain… - JAMA …, 2014 - jamanetwork.com
… In addition to resources included in other studies, we obtained data on intensivists, fully
implemented electronic medical records, and advanced cardiology and found all of them to be …

Surgery versus chemotherapy and radiotherapy for early and locally advanced small cell lung cancer: a propensity-matched analysis of survival

E Wakeam, SA Acuna, NB Leighl, ME Giuliani… - Lung Cancer, 2017 - Elsevier
Background The role of surgery in small cell lung cancer (SCLC) is controversial. Survival
outcomes for resection of stage I-IIIA SCLC compared to chemotherapy-based non-surgical …

[HTML][HTML] COVID-19 guidance for triage of operations for thoracic malignancies: a consensus statement from thoracic surgery outcomes research network

…, V Rusch, L Shulman, TK Varghese, E Wakeam… - The Journal of Thoracic …, 2020 - Elsevier
The extraordinary demands of managing the COVID-19 pandemic has disrupted the world's
ability to care for patients with thoracic malignancies. As a hospital's COVID-19 population …

A 10-gene classifier for distinguishing head and neck squamous cell carcinoma and lung squamous cell carcinoma

…, M Nebozhyn, S Singhal, L Alila, E Wakeam… - Clinical Cancer …, 2007 - AACR
Purpose: The risk of developing metastatic squamous cell carcinoma for patients with head
and neck squamous cell carcinoma (HNSCC) is very high. Because these patients are often …

Gene therapy for mesothelioma and lung cancer

A Vachani, E Moon, E Wakeam… - American journal of …, 2010 - atsjournals.org
Both malignant pleural mesothelioma and advanced stage lung cancer are associated with
a poor prognosis. Unfortunately, current treatment regimens have had only a modest effect …

[HTML][HTML] Optimizing health before elective thoracic surgery: systematic review of modifiable risk factors and opportunities for health services research

SM Stokes, E Wakeam, MB Antonoff… - Journal of Thoracic …, 2019 - ncbi.nlm.nih.gov
Despite progress in many different domains of surgical care, we are still striving toward
practices which will consistently lead to the best care for an increasingly complex surgical …

Risk prediction accuracy differs for emergency versus elective cases in the ACS-NSQIP

JA Hyder, G Reznor, E Wakeam, LL Nguyen… - Annals of …, 2016 - journals.lww.com
… with different event rates (1, 2, and 3) to test for differences in the Brier score and, in addition,
to selecting duplicate elective surgical cohorts (A and B) for tests of the c-statistic and O:E

Risk and patterns of secondary complications in surgical inpatients

E Wakeam, JA Hyder, W Jiang, SA Lipsitz… - JAMA …, 2015 - jamanetwork.com
… Currently, risk prediction strategies typically rely on preoperative data, although some have
begun to formally incorporate intraoperative and postoperative data from electronic health …

Biological basket weaving: formation and function of clathrin-coated vesicles

…, C Knuehl, MC Towler, DE Wakeham - Annual review of cell …, 2001 - annualreviews.org
▪ Abstract There has recently been considerable progress in understanding the regulation of
clathrin-coated vesicle (CCV) formation and function. These advances are due to the …