Neurologic impairment after spinal cord injury (SCI) is currently measured and classified by
functional examination. Biological markers that objectively classify injury severity and predict …

Spinal cord injury typically results in limited functional recovery. Here we investigated whether
therapeutic dietary restriction, a multi-faceted, safe, and clinically-feasible treatment, can …

Creatine kinases are important in maintaining cellular‐energy homeostasis, and
neuroprotective effects have been attributed to the administration of creatine and creatine‐like …

The cytosolic brain-type creatine kinase (BCK) isoform and the mitochondrial ubiquitous
creatine kinase (UbCKmit) isoform are both important for the maintenance and distribution of …

High fat, low carbohydrate ketogenic diets (KD) are validated non-pharmacological
treatments for some forms of drug-resistant epilepsy. Ketones reduce neuronal excitation and …

Large animal and primate models of spinal cord injury (SCI) are being increasingly utilized
for the testing of novel therapies. While these represent intermediary animal species between …

When stimulated strongly, a hair cell's mechanically sensitive hair bundle may consume ATP
too rapidly for replenishment by diffusion. To provide a broad view of the bundle's protein …

Spinal cord injury (SCI) often results in a loss of motor and sensory function. Currently there
are no validated effective clinical treatments. Previously we found in rats that dietary …

One of the major challenges in management of spinal cord injury (SCI) is that the assessment
of injury severity is often imprecise. Identification of reliable, easily quantifiable biomarkers …

Traumatic spinal cord injury (SCI) triggers many perturbations within the injured cord, such
as decreased perfusion, reduced tissue oxygenation, increased hydrostatic pressure, and …