The presence of growth-induced solid stresses in tumors has been suspected for some time,
but these stresses were largely estimated using mathematical models. Solid stresses can …

Osteoid osteoma, a benign bone tumor, has traditionally been treated with operative excision.
A recently developed method for percutaneous ablation of the tumor has been proposed …

Background: Massive endoprostheses provide orthopaedic oncologists with many reconstructive
options after tumor resection, although failure rates are high. Because the number of …

PURPOSE: To report our experience with technical success, complications, and long-term
clinical success of radiofrequency (RF) ablation of osteoid osteoma. MATERIALS AND …

… J Cancer Res Clin Oncol 122:767-769, 1996 29. Bollini G, Jouve JL, Cottalorda … J
Pediatr Orthop B 7:274285, 1998 … Int J Radiat Oncol Biol Phys 49:12431247, 2001 …

The aberrant transcription factor EWS-FLI1 drives Ewing sarcoma, but its molecular function
is not completely understood. We find that EWS-FLI1 reprograms gene regulatory circuits in …

Nonunion of allograft-host junction after bone transplantation is not uncommon, and its
treatment frequently is problematic. To improve the understanding of these nonunions, a …

Solid stress and tissue stiffness affect tumour growth, invasion, metastasis and treatment.
Unlike stiffness, which can be precisely mapped in tumours, the measurement of solid stresses …

PURPOSE: Treatment of extremity soft-tissue sarcomas yields excellent local control, but
distant failure is common with large, high-grade tumors. A regimen of preoperative …

Soft tissue sarcomas are mesenchymal tumors that are fatal in approximately one-third of
patients. To explore mechanisms of sarcoma pathogenesis, we have generated a mouse …